Polycythemia vera: historical oversights, diagnostic details, and therapeutic views
Polycythemia vera (PV) is a relatively indolent myeloid neoplasm with median survival that
exceeds 35 years in young patients, but its natural history might be interrupted by …
exceeds 35 years in young patients, but its natural history might be interrupted by …
Appropriate management of polycythaemia vera with cytoreductive drug therapy: European LeukemiaNet 2021 recommendations
M Marchetti, AM Vannucchi, M Griesshammer… - The Lancet …, 2022 - thelancet.com
Polycythaemia vera is associated with a reduced quality of life, a high rate of vascular
events, and an intrinsic risk of disease evolution. The results of several randomised trials for …
events, and an intrinsic risk of disease evolution. The results of several randomised trials for …
Polycythemia vera: 2024 update on diagnosis, risk‐stratification, and management
Abstract Disease Overview Polycythemia vera (PV) is a JAK2‐mutated myeloproliferative
neoplasm characterized by clonal erythrocytosis; other features include leukocytosis …
neoplasm characterized by clonal erythrocytosis; other features include leukocytosis …
The international consensus classification of myeloid neoplasms and acute leukemias: myeloproliferative neoplasms
J Thiele, HM Kvasnicka, A Orazi… - American journal of …, 2023 - Wiley Online Library
A group of international experts, including hematopathologists, oncologists, and geneticists
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …
Genetic basis and molecular profiling in myeloproliferative neoplasms
D Luque Paz, R Kralovics, RC Skoda - Blood, 2023 - ashpublications.org
Abstract BCR:: ABL1-negative myeloproliferative neoplasms (MPNs) are clonal diseases
originating from a single hematopoietic stem cell that cause excessive production of mature …
originating from a single hematopoietic stem cell that cause excessive production of mature …
Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification
H Pasquer, R Daltro de Oliveira, L Vasseur… - Leukemia, 2024 - nature.com
Current recommended risk scores to predict thrombotic events associated with
myeloproliferative neoplasms (MPN) do not discriminate between arterial and venous …
myeloproliferative neoplasms (MPN) do not discriminate between arterial and venous …
Moving toward disease modification in polycythemia vera
JP Bewersdorf, J How, L Masarova, P Bose… - Blood, 2023 - ashpublications.org
Polycythemia vera (PV) belongs to the BCR-ABL1–negative myeloproliferative neoplasms
and is characterized by activating mutations in JAK2 and clinically presents with …
and is characterized by activating mutations in JAK2 and clinically presents with …
An alternative dosing strategy for ropeginterferon alfa-2b may help improve outcomes in myeloproliferative neoplasms: an overview of previous and ongoing studies …
A Qin, RW Urbanski, L Yu, T Ahmed… - Frontiers in …, 2023 - frontiersin.org
Ropeginterferon alfa-2b is a novel, long-acting mono-pegylated proline-IFN-alpha-2b
approved for treatment of polycythemia vera in adults, regardless of thrombotic risk level or …
approved for treatment of polycythemia vera in adults, regardless of thrombotic risk level or …
[HTML][HTML] Thrombosis in myeloproliferative neoplasms during cytoreductive and antithrombotic drug treatment
A state‐of‐the‐art lecture titled “Myeloproliferative Neoplasm‐associated Thrombosis” was
presented at the ISTH congress in 2021. We summarize here the main points of the lecture …
presented at the ISTH congress in 2021. We summarize here the main points of the lecture …
ROP-ET: a prospective phase III trial investigating the efficacy and safety of ropeginterferon alfa-2b in essential thrombocythemia patients with limited treatment …
JJ Kiladjian, FF Marin, HK Al-Ali, A Alvarez-Larrán… - Annals of …, 2024 - Springer
Interferon-based therapies, such as ropeginterferon alfa-2b have emerged as promising
disease-modifying agents for myeloproliferative neoplasms (MPNs), including essential …
disease-modifying agents for myeloproliferative neoplasms (MPNs), including essential …