SMC complexes differentially compact mitotic chromosomes according to genomic context

SA Schalbetter, A Goloborodko, G Fudenberg… - Nature cell …, 2017 - nature.com
Structural maintenance of chromosomes (SMC) protein complexes are key determinants of
chromosome conformation. Using Hi-C and polymer modelling, we study how cohesin and …

How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes

SK Ghosh, D Jost - PLoS computational biology, 2018 - journals.plos.org
The 3D organization of chromosomes is crucial for regulating gene expression and cell
function. Many experimental and polymer modeling efforts are dedicated to deciphering the …