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Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety
P Breining, AL Frølund, JF Højen… - Basic & clinical …, 2021 - Wiley Online Library
The coronavirus responsible for COVID‐19, SARS‐CoV‐2, utilizes a viral membrane spike
protein for host cell entry. For the virus to engage in host membrane fusion, SARS‐CoV‐2 …
protein for host cell entry. For the virus to engage in host membrane fusion, SARS‐CoV‐2 …
Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches
In the Fall of 2019 a sudden and dramatic outbreak of a pulmonary disease (Coronavirus
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …
Disease COVID-19), due to a new Coronavirus strain (ie, SARS-CoV-2), emerged in the …
Therapeutic strategies against COVID-19 and structural characterization of SARS-CoV-2: a review
The novel coronavirus, SARS-CoV-2, or 2019-nCoV, which originated in Wuhan, Hubei
province, China in December 2019, is a grave threat to public health worldwide. A total of …
province, China in December 2019, is a grave threat to public health worldwide. A total of …
A review on SARS-CoV-2-induced neuroinflammation, neurodevelopmental complications, and recent updates on the vaccine development
Abstract Coronavirus disease 2019 (COVID-19) is a devastating viral infection caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The incidence and …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The incidence and …
[HTML][HTML] Potential anti-COVID-19 therapeutics that block the early stage of the viral life cycle: structures, mechanisms, and clinical trials
RA Al-Horani, S Kar, KF Aliter - International Journal of Molecular …, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease-2019 (COVID-19) is being caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease continues to present …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The disease continues to present …
High-throughput virtual screening approach of natural compounds as target inhibitors of plasmepsin-II
Plasmepsin II is a key enzyme in the life cycle of the Plasmodium falciparum parasite
responsible for malaria, a disease that is causing deaths on a worldwide scale. Recently …
responsible for malaria, a disease that is causing deaths on a worldwide scale. Recently …
Challenges and toxicity assessment of inorganic nanomaterials in biomedical applications: Current status and future roadmaps
Nano-world is expanding rapidly due to the amalgamation of different science disciplines.
Nanomaterials (NMs) have wide applications in the biomedical field due to their unique …
Nanomaterials (NMs) have wide applications in the biomedical field due to their unique …
[HTML][HTML] Discovery of novel TMPRSS2 inhibitors for COVID-19 using in silico fragment-based drug design, molecular docking, molecular dynamics, and quantum …
AA Alzain, FA Elbadwi, FO Alsamani - Informatics in Medicine Unlocked, 2022 - Elsevier
The global expansion of COVID-19 and the mutations of severe acute respiratory syndrome
coronavirus necessitate quick development of treatment and vaccination. Because the …
coronavirus necessitate quick development of treatment and vaccination. Because the …
[PDF][PDF] COVID-19: Fisiopatologia e alvos para intervenção terapêutica
JO De Almeida, VRT De Oliveira, JLS Avelar… - Revista virtual de …, 2020 - academia.edu
The pandemic status of COVID-19 was recorded by the World Health Organization (WHO)
on March 11, 2020. Since then, more than 10 million cases have been confirmed worldwide …
on March 11, 2020. Since then, more than 10 million cases have been confirmed worldwide …
Spiking dependence of SARS‐CoV‐2 pathogenicity on TMPRSS2
AZ Abbasi, DA Kiyani, SM Hamid… - Journal of Medical …, 2021 - Wiley Online Library
Epidemiological data shows a discrepancy in COVID‐19 susceptibility and outcomes with
some regions being more heavily affected than others. However, the factors that determine …
some regions being more heavily affected than others. However, the factors that determine …