Abstract Background and Purpose This update of the treatment guidelines was
commissioned by the European Academy of Neurology and the European section of the …

Although dopamine replacement therapy remains a core component of Parkinson's disease
treatment, the onset of motor fluctuations and dyskinetic movements might require a range of …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Background: Tremor is one of the most prevalent symptoms in Parkinson's Disease (PD).
The progression and management of tremor in PD can be challenging, as response to …

Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

Background: As a chronic and progressive neurodegenerative disease, Parkinson's disease
(PD) still lacks effective and safe targeted drug therapy. Low-intensity focused ultrasound …