Dopamine and cognitive control in prefrontal cortex
Cognitive control, the ability to orchestrate behavior in accord with our goals, depends on
the prefrontal cortex. These cognitive functions are heavily influenced by the …
the prefrontal cortex. These cognitive functions are heavily influenced by the …
Role of dopamine receptors in ADHD: a systematic meta-analysis
J Wu, H **ao, H Sun, L Zou, LQ Zhu - Molecular neurobiology, 2012 - Springer
The dopaminergic system plays a pivotal role in the central nervous system via its five
diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many …
diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many …
Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders
A Annamneedi, C Gora, A Dudas… - British journal of …, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …
core symptoms: deficits in social interaction and communication, and stereotyped …
Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex
Dopamine D2 receptors (D2Rs) play a major role in the function of the prefrontal cortex
(PFC), and may contribute to prefrontal dysfunction in conditions such as schizophrenia …
(PFC), and may contribute to prefrontal dysfunction in conditions such as schizophrenia …
Additive effects of genetic variation in dopamine regulating genes on working memory cortical activity in human brain
Functional polymorphisms in the catechol-O-methyltransferase (COMT) and the dopamine
transporter (DAT) genes modulate dopamine inactivation, which is crucial for determining …
transporter (DAT) genes modulate dopamine inactivation, which is crucial for determining …
Requirement of dopamine signaling in the amygdala and striatum for learning and maintenance of a conditioned avoidance response
Two-way active avoidance (2WAA) involves learning Pavlovian (association of a sound cue
with a foot shock) and instrumental (shock avoidance) contingencies. To identify regions …
with a foot shock) and instrumental (shock avoidance) contingencies. To identify regions …
The ability of the mesocortical dopamine system to operate in distinct temporal modes
Background This review discusses evidence that cells in the mesocortical dopamine (DA)
system influence information processing in target areas across three distinct temporal …
system influence information processing in target areas across three distinct temporal …
Modulation of synaptic plasticity in the cortex needs to understand all the players
CNJ Meunier, P Chameau, PM Fossier - Frontiers in synaptic …, 2017 - frontiersin.org
The prefrontal cortex (PFC) is involved in cognitive tasks such as working memory, decision
making, risk assessment and regulation of attention. These functions performed by the PFC …
making, risk assessment and regulation of attention. These functions performed by the PFC …
D1 and D2 dopamine receptors in separate circuits cooperate to drive associative long-term potentiation in the prefrontal cortex
TX Xu, WD Yao - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Dopamine release associated with motivational arousal is thought to drive goal-directed
learning and consolidation of acquired memories. This dopamine hypothesis of learning and …
learning and consolidation of acquired memories. This dopamine hypothesis of learning and …
Dopaminergic signaling in dendritic spines
WD Yao, RD Spealman, J Zhang - Biochemical pharmacology, 2008 - Elsevier
Dopamine regulates movement, motivation, reward, and learning and is implicated in
numerous neuropsychiatric and neurological disorders. The action of dopamine is mediated …
numerous neuropsychiatric and neurological disorders. The action of dopamine is mediated …