Metabolic syndrome: updates on pathophysiology and management in 2021
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …
From pre-diabetes to diabetes: diagnosis, treatments and translational research
Diabetes, a silent killer, is one of the most widely prevalent conditions of the present time.
According to the 2017 International Diabetes Federation (IDF) statistics, the global …
According to the 2017 International Diabetes Federation (IDF) statistics, the global …
Senescence and aging: Causes, consequences, and therapeutic avenues
D McHugh, J Gil - Journal of Cell Biology, 2018 - rupress.org
Aging is the major risk factor for cancer, cardiovascular disease, diabetes, and
neurodegenerative disorders. Although we are far from understanding the biological basis of …
neurodegenerative disorders. Although we are far from understanding the biological basis of …
[HTML][HTML] Diabetes mellitus: The epidemic of the century
The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …
[HTML][HTML] Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis
Background Plasma insulin levels are predominantly the product of the morphological mass
of insulin producing beta cells in the pancreatic islets of Langerhans and the functional …
of insulin producing beta cells in the pancreatic islets of Langerhans and the functional …
[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism
T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …
[HTML][HTML] Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention
Y Wu, Y Ding, Y Tanaka, W Zhang - International journal of medical …, 2014 - ncbi.nlm.nih.gov
Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and …
inheritance-environment interaction along with other risk factors such as obesity and …
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals
Metabolic diseases are the most common and rapidly growing health issues worldwide. The
massive population-based human genetics is crucial for the precise prevention and …
massive population-based human genetics is crucial for the precise prevention and …
Prevention of diabetes and cardiovascular disease in obesity
L La Sala, AE Pontiroli - International journal of molecular sciences, 2020 - mdpi.com
Obesity is one of the major risk factors for the development of both impaired glucose
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …
The functions of metallothionein and ZIP and ZnT transporters: an overview and perspective
T Kimura, T Kambe - International journal of molecular sciences, 2016 - mdpi.com
Around 3000 proteins are thought to bind zinc in vivo, which corresponds to~ 10% of the
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …