The liver is the only solid organ that uses regenerative mechanisms to ensure that the liver-
to-bodyweight ratio is always at 100% of what is required for body homeostasis. Other solid …

Inflammation is a complex and necessary component of the response to biological,
chemical, or physical stimuli, and the cellular and molecular events that initiate and regulate …

In contrast to all other organs, liver‐to‐body‐weight ratio needs to be maintained always at
100% of what is required for body homeostasis. Adjustment of liver size to 100% of what is …

Hepatocytes, the major parenchymal cells in the liver, play pivotal roles in metabolism,
detoxification, and protein synthesis. Hepatocytes also activate innate immunity against …

An understanding of connections between gut microbiome and liver has provided important
insights into the pathophysiology of liver diseases. Since gut microbial dysbiosis increases …

Signals related to liver regeneration (LR) have been identified by triggering proliferation in
hepatocyte cultures, delay of regeneration associated with signal ablation in genomically …

The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver
disease than in those without liver disease and osteoporosis and sarcopenia negatively …

Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …

The mechanism of how plant-derived nanovesicles are uptaken by cells remains unknown.
In this study, the garlic-derived nanovesicles (GDVs) were isolated and digested with trypsin …

Osteoporosis is a frequently observed complication in patients with chronic liver disease,
particularly liver cirrhosis and cholestatic liver diseases. In addition, osteoporosis is critical in …