Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Tracking of extracellular vesicles' biodistribution: new methods and approaches
AM Aimaletdinov, MO Gomzikova - International Journal of Molecular …, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are released by almost
all cell types. They range in diameter from 30 nm to several micrometres and have the ability …
all cell types. They range in diameter from 30 nm to several micrometres and have the ability …
Surface enhanced Raman scattering of extracellular vesicles for cancer diagnostics despite isolation dependent lipoprotein contamination
HJ Koster, T Rojalin, A Powell, D Pham, RR Mizenko… - Nanoscale, 2021 - pubs.rsc.org
Given the emerging diagnostic utility of extracellular vesicles (EVs), it is important to account
for non-EV contaminants. Lipoprotein present in EV-enriched isolates may inflate particle …
for non-EV contaminants. Lipoprotein present in EV-enriched isolates may inflate particle …
Nanoscopic and functional characterization of keratinocyte-originating exosomes in the wound fluid of non-diabetic and diabetic chronic wound patients
PR Guda, A Sharma, AJ Anthony, MS El Masry… - Nano Today, 2023 - Elsevier
Exosomes, a class of extracellular vesicles of endocytic origin, play a critical role in
paracrine signaling for successful cell-cell crosstalk in vivo. However, limitations in our …
paracrine signaling for successful cell-cell crosstalk in vivo. However, limitations in our …
Droplet detection and sorting system in microfluidics: a review
Since being invented, droplet microfluidic technologies have been proven to be perfect tools
for high-throughput chemical and biological functional screening applications, and they …
for high-throughput chemical and biological functional screening applications, and they …
Recent advances in optical label-free characterization of extracellular vesicles
Extracellular vesicles (EVs) are complex biological nanoparticles endogenously secreted by
all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids …
all eukaryotic cells. EVs carry a specific molecular cargo of proteins, lipids, and nucleic acids …
[HTML][HTML] Cancer diagnosis using label-free SERS-based exosome analysis
Exosomes, carrying distinctive biomolecules reflective of their parent cell's status and origin,
show promise as liquid biopsy biomarkers for cancer diagnosis. However, their clinical …
show promise as liquid biopsy biomarkers for cancer diagnosis. However, their clinical …
Characterization of ovarian cancer-derived extracellular vesicles by surface-enhanced Raman spectroscopy
Ovarian cancer is the most lethal gynecological malignancy, owing to the fact that most
cases are diagnosed at a late stage. To improve prognosis and reduce mortality, we must …
cases are diagnosed at a late stage. To improve prognosis and reduce mortality, we must …
A new detection method of oral and oropharyngeal squamous cell carcinoma based on multivariate analysis of surface enhanced raman spectra of salivary exosomes
Raman spectroscopy recently proved a tremendous capacity to identify disease-specific
markers in various (bio) samples being a non-invasive, rapid, and reliable method for cancer …
markers in various (bio) samples being a non-invasive, rapid, and reliable method for cancer …
Emerging biosensing platforms for quantitative detection of exosomes as diagnostic biomarkers
J Tan, Y Wen, M Li - Coordination Chemistry Reviews, 2021 - Elsevier
Exosomes are a class of extracellular vesicles secreted by all living cells. Exosomes carry
abundant constituents from their parental cells that are proteins, nucleic acids, lipids, small …
abundant constituents from their parental cells that are proteins, nucleic acids, lipids, small …