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Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers
S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …
Multifunctional biomolecule nanostructures for cancer therapy
J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs
J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
Nanomedicine for increasing the oral bioavailability of cancer treatments
Oral administration is an appealing route of delivering cancer treatments. However, the
gastrointestinal tract is characterized by specific and efficient physical, chemical, and …
gastrointestinal tract is characterized by specific and efficient physical, chemical, and …
Review of the role of nanotechnology in overcoming the challenges faced in oral cancer diagnosis and treatment
Throughout the world, oral cancer is a common and aggressive malignancy with a high risk
of morbidity, mortality, and recurrence. The importance of early detection in cancer …
of morbidity, mortality, and recurrence. The importance of early detection in cancer …
Towards the future exploration of mucosal mRNA vaccines against emerging viral diseases; lessons from existing next-generation mucosal vaccine strategies
The mRNA vaccine platform has offered the greatest potential in fighting the COVID-19
pandemic owing to rapid development, effectiveness, and scalability to meet the global …
pandemic owing to rapid development, effectiveness, and scalability to meet the global …
Oral vaccines: a better future of immunization
KWY Kwong, Y **n, NCY Lai, JCC Sung, KC Wu… - Vaccines, 2023 - mdpi.com
Oral vaccines are gaining more attention due to their ease of administration, lower
invasiveness, generally greater safety, and lower cost than injectable vaccines. This review …
invasiveness, generally greater safety, and lower cost than injectable vaccines. This review …
[HTML][HTML] Translational challenges and prospective solutions in the implementation of biomimetic delivery systems
Biomimetic delivery systems (BDSs), inspired by the intricate designs of biological systems,
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …
Current trends of targeted drug delivery for oral cancer therapy
M Zhang, J Liang, Y Yang, H Liang, H Jia… - … in bioengineering and …, 2020 - frontiersin.org
Oral cancer is an aggressive tumor that invades the local tissue and can cause metastasis
and high mortality. Conventional treatment strategies, eg, surgery, chemotherapy, and …
and high mortality. Conventional treatment strategies, eg, surgery, chemotherapy, and …
Engineering a nanoscale Al‐MOF‐armored antigen carried by a “trojan horse”‐like platform for oral vaccination to induce potent and long‐lasting immunity
YB Miao, WY Pan, KH Chen, HJ Wei… - Advanced Functional …, 2019 - Wiley Online Library
Vaccination via the oral administration of an antigen faces many challenges, including
gastrointestinal (GI) proteolysis and mucosal barriers. To limit GI proteolysis, a …
gastrointestinal (GI) proteolysis and mucosal barriers. To limit GI proteolysis, a …