Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …

Simple Summary Chronic myeloid leukemia (CML) is a myeloproliferative neoplasia
associated with a molecular alteration, the fusion gene BCR-ABL1, that encodes the tyrosine …

Ethnopharmacological relevance Osteoporosis is a chronic epidemic which can leads to
enhanced bone fragility and consequent an increase in fracture risk. Traditional Chinese …

Inflammation is closely related with the progression of cancer and is an indispensable
component that orchestrates the tumor microenvironment. Studies suggest that different …

The ERK/MAPK cascade is one the four distinctive MAPK cascades which transmit
extracellular signals to intracellular targets. This cascade has an important role in the …

MicroRNAs (miRNAs) as the regulatory short noncoding RNAs are involved in a wide array
of cellular and molecular processes. They negatively regulate gene expression and their …

The exploration of an effective diabetic chronic wound healing process still remains a great
challenge. Herein, we used gene overexpression technology to obtain synovial …

Medical practitioners are recommending combination therapy in cancer for its various
advantages. Combination therapy increases the efficacy of treatment due to its synergistic …

Pre-eclampsia is a pregnancy-related disease that may cause maternal, neonatal and fetal
morbidity and mortality and exists in 3–5% of pregnancies worldwide. The discovery of …

Background Cancer, as one of the main causes of human deaths, is currently a significant
global health challenge. Since the majority of cancer-related deaths are associated with late …