Advances in pathogenesis and therapeutic strategies for osteoporosis

S Song, Y Guo, Y Yang, D Fu - Pharmacology & therapeutics, 2022 - Elsevier
Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

Recent advances refining galactooligosaccharide production from lactose

A Gosling, GW Stevens, AR Barber, SE Kentish… - Food chemistry, 2010 - Elsevier
The production of prebiotic galactooligosaccharides (GOS) by the β-galactosidase catalysed
conversion of lactose has become commercially important. Yet it remains a challenge to …

Roles of pgaABCD Genes in Synthesis, Modification, and Export of the Escherichia coli Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine

Y Itoh, JD Rice, C Goller, A Pannuri, J Taylor… - Journal of …, 2008 - journals.asm.org
The linear homopolymer poly-β-1, 6-N-acetyl-d-glucosamine (β-1, 6-GlcNAc; PGA) serves
as an adhesin for the maintenance of biofilm structural stability in diverse eubacteria. Its …

Galacto-oligosaccharide production using microbial β-galactosidase: current state and perspectives

AR Park, DK Oh - Applied Microbiology and Biotechnology, 2010 - Springer
Galacto-oligosaccharides have become the focus of a great deal of attention in the field of
functional foods, owing to their known health benefits and potential to improve the quality of …

Bifidobacterium longum subsp. infantis uses two different β-galactosidases for selectively degrading type-1 and type-2 human milk oligosaccharides

E Yoshida, H Sakurama, M Kiyohara, M Nakajima… - …, 2012 - academic.oup.com
The breast-fed infant intestine is often colonized by particular bifidobacteria, and human milk
oligosaccharides (HMOs) are considered to be bifidogenic. Recent studies showed that …

[HTML][HTML] Bifidobacterial enzymes involved in the metabolism of human milk oligosaccharides

M Kitaoka - Advances in nutrition, 2012 - Elsevier
Intestinal colonization of bifidobacteria is important for the health of infants. Human milk
oligosaccharides (HMO) have been identified as growth factors for bifidobacteria. Recently …

Crystal structure of human β-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases

U Ohto, K Usui, T Ochi, K Yuki, Y Satow… - Journal of biological …, 2012 - jbc.org
G M1 gangliosidosis and Morquio B are autosomal recessive lysosomal storage diseases
associated with a neurodegenerative disorder or dwarfism and skeletal abnormalities …

Understanding high-salt and cold adaptation of a polyextremophilic enzyme

R Karan, S Mathew, R Muhammad, DB Bautista… - Microorganisms, 2020 - mdpi.com
The haloarchaeon Halorubrum lacusprofundi is among the few polyextremophilic organisms
capable of surviving in one of the most extreme aquatic environments on Earth, the Deep …

Unique sugar metabolic pathways of bifidobacteria

S Fushinobu - Bioscience, biotechnology, and biochemistry, 2010 - Taylor & Francis
Bifidobacteria have many beneficial effects for human health. The gastrointestinal tract,
where natural colonization of bifidobacteria occurs, is an environment poor in nutrition and …

[HTML][HTML] Cold-active β-galactosidases: insight into cold adaptation mechanisms and biotechnological exploitation

M Mangiagalli, M Lotti - Marine Drugs, 2021 - mdpi.com
β-galactosidases (EC 3.2. 1.23) catalyze the hydrolysis of β-galactosidic bonds in
oligosaccharides and, under certain conditions, transfer a sugar moiety from a glycosyl …