Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …

Manganese is both an essential nutrient and a potential neurotoxicant. Therefore, the
question arises whether the dietary manganese intake in the German population is on the …

Highlights•MnCl 2 induces biochemical changes in the brain: reduction of monoamines and
disturbing the imbalance between excitatory and inhibitory neurotransmitters.•MnCl 2 …

Following a request from the European Commission (EC), the EFSA Panel on Nutrition,
Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the …

Acute exposure to manganese is associated with complex behavioral/psychiatric signs that
may include Parkinsonian motor features. However, little is known about the behavioral …

Airborne metal-containing particles represent a known source of health risk but the role of
nano-sized particles in the pathogenicity of dust has been recognized only recently. As a …

Incomplete information on toxicological differences of micro-and nanometer-sized particles
raised concerns about the effects of the latter on health and environment. Besides chemical …

Abstract Lead (Pb), arsenic (As) and manganese (Mn) are neurotoxic elements that often
occur in mixtures for which practically no information is available on biomarkers (BMs) for …

The toxicity of manganese-containing airborne particles is an important occupational and
environmental problem. In this work, adult male Wistar rats were treated with a …

YAC128 Huntington's disease (HD) transgenic mice accumulate less manganese (Mn) in
the striatum relative to wild-type (WT) littermates. We hypothesized that Mn and mutant …