Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Small-molecule fluorescence-based probes for interrogating major organ diseases
Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …
organ-related processes at the cellular level are of great importance in biological research …
Stimulus-cleavable chemistry in the field of controlled drug delivery
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …
owing to their capability of achieving exquisite control over drug release via the exposure to …
Chemiluminescent Probes with Long‐Lasting High Brightness for In Vivo Imaging of Neutrophils
Real‐time optical imaging of immune cells can contribute to understanding their
pathophysiological roles, which still remains challenging. Current sensitive …
pathophysiological roles, which still remains challenging. Current sensitive …
Fluorescent probes for visualizing ROS-associated proteins in disease
Abnormal expression of proteins, including catalytic and expression dysfunction, is directly
related to the development of various diseases in living organisms. Reactive oxygen species …
related to the development of various diseases in living organisms. Reactive oxygen species …
Multienzyme-targeted fluorescent probe as a biosensing platform for broad detection of pesticide residues
WY Guo, YX Fu, SY Liu, LC Mei, Y Sun, J Yin… - Analytical …, 2021 - ACS Publications
Pesticide residues, significantly hampering the overall environmental and human health,
have become an increasingly severe issue. Thus, develo** rapid, cost-effective, and …
have become an increasingly severe issue. Thus, develo** rapid, cost-effective, and …
Peptide probes for proteases–innovations and applications for monitoring proteolytic activity
M Rodriguez-Rios, A Megia-Fernandez… - Chemical Society …, 2022 - pubs.rsc.org
Proteases are excellent biomarkers for a variety of diseases, offer multiple opportunities for
diagnostic applications and are valuable targets for therapy. From a chemistry-based …
diagnostic applications and are valuable targets for therapy. From a chemistry-based …
Near-infrared fluorescent probes for the detection of cancer-associated proteases
JI Scott, Q Deng, M Vendrell - ACS chemical biology, 2021 - ACS Publications
Proteases are enzymes capable of catalyzing protein breakdown, which is critical across
many biological processes. There are several families of proteases, each of which perform …
many biological processes. There are several families of proteases, each of which perform …
Multifunctional fluorescent probe for simultaneously detecting microviscosity, micropolarity, and carboxylesterases and its application in bioimaging
YL Qi, HR Wang, LL Chen, B Yang, YS Yang… - Analytical …, 2022 - ACS Publications
Based on OR logic gate, we proposed a smart near-infrared (NIR) fluorescent probe, named
VPCPP, for simultaneously monitoring local microviscosity, micropolarity, and …
VPCPP, for simultaneously monitoring local microviscosity, micropolarity, and …
Emerging biomaterials imaging antitumor immune response
Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …