The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Streptococcus pneumoniae: transmission, colonization and invasion

JN Weiser, DM Ferreira, JC Paton - Nature Reviews Microbiology, 2018 - nature.com
Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Endoscope-assisted magnetic helical micromachine delivery for biofilm eradication in tympanostomy tube

Y Dong, L Wang, Z Zhang, F Ji, TKF Chan, H Yang… - Science …, 2022 - science.org
Occlusion of the T-tube (tympanostomy tube) is a common postoperative sequela related to
bacterial biofilms. Confronting biofilm-related infections of T-tubes, maneuverable and …

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

M Malone, T Bjarnsholt, AJ McBain… - Journal of wound …, 2017 - magonlinelibrary.com
The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …

Otitis media

AGM Schilder, T Chonmaitree, AW Cripps… - Nature reviews Disease …, 2016 - nature.com
Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis
media (AOM), otitis media with effusion (OME;'glue ear') and chronic suppurative otitis media …

Bacterial biofilms in the human body: Prevalence and impacts on health and disease

EK Perry, MW Tan - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Bacterial biofilms can be found in most environments on our planet, and the human body is
no exception. Consisting of microbial cells encased in a matrix of extracellular polymers …

Healthcare-associated infections, medical devices and biofilms: risk, tolerance and control

SL Percival, L Suleman, C Vuotto… - Journal of medical …, 2015 - microbiologyresearch.org
Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …

[HTML][HTML] ESCMID guideline for the diagnosis and treatment of biofilm infections 2014

N Høiby, T Bjarnsholt, C Moser, GL Bassi… - Clinical microbiology …, 2015 - Elsevier
Biofilms cause chronic infections in tissues or by develo** on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …