Amygdalin potentiates the anti-cancer effect of Sorafenib on Ehrlich ascites carcinoma and ameliorates the associated liver damage

AA Attia, AF Salama, JG Eldiasty, SAER Mosallam… - Scientific Reports, 2022 - nature.com
The burden of cancer diseases is increasing every year, therefore, the demands to figure out
novel drugs that can retain antitumor properties have been raised. This study aimed to …

Camel milk extracellular vesicles/exosomes: a fascinating frontier in isolation and therapeutic potential

AA Badawy, SM El-Hofey, AM Shaban, SE Orif… - Food & Function, 2025 - pubs.rsc.org
Camel milk has a unique composition that sets it apart from other types of animal milk, which
has captured the interest of medical and scientific communities. Extracellular vesicles (EVs) …

Chitosan nanoparticles, camel milk exosomes and/or Sorafenib induce apoptosis, inhibit tumor cells migration and angiogenesis and ameliorate the associated liver …

AA Tawfic, HM Ibrahim, K Mohammed-Geba… - Beni-Suef University …, 2024 - Springer
Background It is crucial to improve cancer patients' quality of life by develo** medications
that can treat cancer with minimum adverse effects. This study aimed to evaluate the …

[HTML][HTML] Quercetin alleviated multi-walled carbon nanotubes-induced neurotoxicity in mice through inhibition of oxidation, inflammation, and pyroptosis

AA Sallam, MA El-Magd, MM Ahmed, HI Ghamry… - Biomedicine & …, 2022 - Elsevier
Recently, we reported that quercetin (Que) could alleviate immunotoxicity induced by
pristine multi-walled carbon nanotubes (MWCNTs) in mice. In the present study, we …

Walnut kernel oil and defatted extracts enhance mesenchymal stem cell stemness and delay senescence

MA Elsied, ZW Sharawi, H Al-Amrah, RA Hegazy… - Molecules, 2023 - mdpi.com
Decreased stemness and increased cellular senescence impair the ability of mesenchymal
stem cells (MSCs) to renew themselves, change into different cell types, and contribute to …

Protocatechuic acid-based supramolecular hydrogel targets serpinB9 to achieve local chemotherapy for OSCC

Z Li, L Cao, C Yang, T Liu, H Zhao, X Luo… - ACS Applied Materials …, 2022 - ACS Publications
Protocatechuic acid (PCA) is a natural phenolic acid present in daily vegetables and fruits.
Notably, PCA was demonstrated to inhibit the biological function of SerpinB9 (Sb9) and …

Isolation, identification, and characterization of α- asarone, from hydromethanolic leaf extract of Acorus calamus L. and its apoptosis-inducing mechanism in A549 …

AB Thakkar, RB Subramanian, SS Thakkar… - Journal of …, 2024 - Taylor & Francis
Due to the presence of several active secondary metabolites, the traditional Indian and
Chinese medicinal herb Acorus calamus L. has been utilized for both medical and culinary …

Revisiting edible insects as sources of therapeutics and drug delivery systems for cancer therapy

B Sinha, Y Choudhury - Frontiers in Pharmacology, 2024 - frontiersin.org
Cancer has been medicine's most formidable foe for long, and the rising incidence of the
disease globally has made effective cancer therapy a significant challenge. Drug discovery …

Ameliorative effects of camel milk and its exosomes on diabetic nephropathy in rats

AM Shaban, M Raslan, SH Qahl, K Elsayed… - Membranes, 2022 - mdpi.com
Contradictory results were obtained regarding the effects of extracellular vesicles such as
exosomes (EXOs) on diabetes and diabetic nephropathy (DN). Some studies showed that …

Quercetin-ameliorated, multi-walled carbon nanotubes-induced immunotoxic, inflammatory, and oxidative effects in mice

AA Sallam, MM Ahmed, MA El-Magd, A Magdy… - Molecules, 2022 - mdpi.com
The expanding uses of carbon nanotubes (CNTs) in industry and medicine have raised
concerns about their toxicity on human and animal health. CNTs, including multi-walled …