[HTML][HTML] Greasing the wheels of the cancer machine: the role of lipid metabolism in cancer

MT Snaebjornsson, S Janaki-Raman, A Schulze - Cell metabolism, 2020 - cell.com
Altered lipid metabolism is among the most prominent metabolic alterations in cancer.
Enhanced synthesis or uptake of lipids contributes to rapid cancer cell growth and tumor …

Trends and advances in sustainable bioethanol production technologies from first to fourth generation: a critical review

MAK Joyia, M Ahmad, YF Chen, M Mustaqeem… - Energy Conversion and …, 2024 - Elsevier
By the end of 2050, the world population is anticipated to reach 10 billion, which will change
the perception of energy utilization. In recent years, the reliance on fossil fuels has shifted …

iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer

DS Park, T Kozaki, SK Tiwari, M Moreira… - Nature, 2023 - nature.com
Microglia are specialized brain-resident macrophages that arise from primitive macrophages
colonizing the embryonic brain. Microglia contribute to multiple aspects of brain …

A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression

MP Plebanek, Y Xue, YV Nguyen, NC DeVito… - Science …, 2024 - science.org
Conventional dendritic cells (DCs) are essential mediators of antitumor immunity. As a
result, cancers have developed poorly understood mechanisms to render DCs dysfunctional …

Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluorooctane sulfonic acid (PFOS) and …

Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism

R Bertolio, F Napoletano, M Mano… - Nature …, 2019 - nature.com
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …

[HTML][HTML] Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

K Bensaad, E Favaro, CA Lewis, B Peck, S Lord… - Cell reports, 2014 - cell.com
An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

F Baenke, B Peck, H Miess… - Disease models & …, 2013 - journals.biologists.com
An increased rate of lipid synthesis in cancerous tissues has long been recognised as an
important aspect of the rewired metabolism of transformed cells. However, the contribution of …

Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Lipid metabolism in cancer

CR Santos, A Schulze - The FEBS journal, 2012 - Wiley Online Library
Lipids form a diverse group of water‐insoluble molecules that include triacylglycerides,
phosphoglycerides, sterols and sphingolipids. They play several important roles at cellular …