One-carbon metabolism in neurodevelopmental disorders: using broad-based nutraceutics to treat cognitive deficits in complex spectrum disorders

L Schaevitz, J Berger-Sweeney, L Ricceri - Neuroscience & Biobehavioral …, 2014 - Elsevier
Folate and choline, two nutrients involved in the one-carbon metabolic cycle, are intimately
involved in regulating DNA integrity, synthesis, biogenic amine synthesis, and methylation …

Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency

MS Field, E Kamynina, OC Agunloye… - Journal of Biological …, 2014 - ASBMB
Folate-mediated one-carbon metabolism is a metabolic network of interconnected pathways
that is required for the de novo synthesis of three of the four DNA bases and the …

Homicide or happiness: did folate fortification and public health campaigns influence homicide rates and the Great American Crime Decline?

SJ Schoenthaler, SL Prescott, AC Logan - Nutrients, 2024 - mdpi.com
The last several years have witnessed a remarkable growth in research directed at nutrition
and behavior, with increased interest in the field of nutritional criminology. It is becoming …

Do methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 polymorphisms modify changes in intelligence of school-age …

Z Feng, N An, F Yu, J Ma, N Li, Y Du, M Guo… - Chinese Medical …, 2022 - mednexus.org
Background: Excessive exposure to fluoride can reduce intelligence.
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate …

Attributes of conscientiousness throughout the animal kingdom: An empirical and evolutionary overview.

MM Delgado, FJ Sulloway - Psychological bulletin, 2017 - psycnet.apa.org
Conscientiousness is a fundamental aspect of human personality, one that is closely linked
with various favorable life outcomes. Despite its importance in humans, conscientiousness …

Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice

E Pjetri, SH Zeisel - Behavioural Brain Research, 2017 - Elsevier
The MTHFD1 gene encodes for methylenetetrahydrofolate dehydrogenase 1, an enzyme
that has an important role in folate-mediated one-carbon metabolism. In people, a single …

Impulsive-like behavior: A review of animal models.

G Chirinéa, A Gouveia Jr - Psychology & Neuroscience, 2019 - psycnet.apa.org
Impulsivity is a component of several psychiatric disorders including attention-
deficit/hyperactivity disorder (ADHD) and substance abuse. Different operational definitions …

[BOOK][B] One-carbon metabolism nutrients and DNA methylation in individuals with Anorexia Nervosa

J Burdo - 2019 - search.proquest.com
Background: Anorexia Nervosa (AN) is a serious psychiatric illness, characterized by a
phobia of weight gain resulting in low weight or malnutrition. DNA methylation, an epigenetic …

[PDF][PDF] Impulsive-like Behavior: a Review of Animal Models Guilherme Chirinéa Universidade Federal da Bahia Universidade Federal do Pará

A Gouveia Jr - 2018 - academia.edu
Impulsivity is a component of several psychiatric disorders including attention
deficit/hyperactivity disorder (ADHD) and substance abuse. Different operational definitions …