Updated international consensus report on the investigation and management of primary immune thrombocytopenia

D Provan, DM Arnold, JB Bussel, BH Chong… - Blood …, 2019 - ashpublications.org
Over the last decade, there have been numerous developments and changes in treatment
practices for the management of patients with immune thrombocytopenia (ITP). This article is …

International consensus report on the investigation and management of primary immune thrombocytopenia

D Provan, R Stasi, AC Newland… - Blood, The Journal …, 2010 - ashpublications.org
Previously published guidelines for the diagnosis and management of primary immune
thrombocytopenia (ITP) require updating largely due to the introduction of new classes of …

Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working …

F Rodeghiero, R Stasi, T Gernsheimer… - Blood, The Journal …, 2009 - ashpublications.org
Diagnosis and management of immune thrombocytopenic purpura (ITP) remain largely
dependent on clinical expertise and observations more than on evidence derived from …

Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing

SL Smith, PR Kennedy, KB Stacey… - Blood …, 2020 - ashpublications.org
Children with immune thrombocytopenia (ITP) rarely suffer from life-threatening bleeds (eg,
intracranial hemorrhage). In such settings, the combination of IV methylprednisolone (IVMP) …

Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study

JB Bussel, PG de Miguel, JM Despotovic… - The Lancet …, 2015 - thelancet.com
Background The oral thrombopoietin receptor agonist eltrombopag is approved for treatment
of adults with chronic immune thrombocytopenia. In the PETIT trial, we aimed to investigate …

A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia

JB Bussel, GR Buchanan, DJ Nugent… - Blood, The Journal …, 2011 - ashpublications.org
Romiplostim, a thrombopoietin-mimetic peptibody, increases and maintains platelet counts
in adults with immune thrombocytopenia (ITP). In this first study of a thrombopoietic agent in …

Romiplostim in children with immune thrombocytopenia: a phase 3, randomised, double-blind, placebo-controlled study

MD Tarantino, JB Bussel, VS Blanchette, J Despotovic… - The Lancet, 2016 - thelancet.com
Background The thrombopoietin receptor agonist romiplostim could be an effective
treatment in symptomatic children with persistent or chronic immune thrombocytopenia. We …

Epidemiology and clinical manifestations of immune thrombocytopenia

R Kohli, S Chaturvedi - Hämostaseologie, 2019 - thieme-connect.com
Immune thrombocytopenia (ITP) occurs with an incidence rate of 1.6 to 3.9 per 100,000
patient-years, which increases with age and has a slight female preponderance. ITP is …

Severe hemorrhage in children with newly diagnosed immune thrombocytopenic purpura

CE Neunert, GR Buchanan, P Imbach… - Blood, The Journal …, 2008 - ashpublications.org
Controversy exists regarding management of children newly diagnosed with immune
thrombocytopenic purpura (ITP). Drug treatment is usually administered to prevent severe …

Eltrombopag for use in children with immune thrombocytopenia

TO Kim, J Despotovic, MP Lambert - Blood advances, 2018 - ashpublications.org
Eltrombopag is currently the only US Food and Drug Administration–approved
thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia (ITP) …