Lateral flow test engineering and lessons learned from COVID-19
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
Recent advances in point-of-care testing of COVID-19
S Lee, L Bi, H Chen, D Lin, R Mei, Y Wu… - Chemical Society …, 2023 - pubs.rsc.org
Advances in microfluidic device miniaturization and system integration contribute to the
development of portable, handheld, and smartphone-compatible devices. These …
development of portable, handheld, and smartphone-compatible devices. These …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
Recent progress of smartphone-assisted microfluidic sensors for point of care testing
G **ng, J Ai, N Wang, Q Pu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Point of care (POC) testing is of great importance in rapid diagnosis of disease, monitoring
environmental pollutants, food safety analysis and other fields, especially in resource-limited …
environmental pollutants, food safety analysis and other fields, especially in resource-limited …
Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens
Deployment of nucleic acid amplification assays for diagnosing pathogens in point-of-care
settings is a challenge due to lengthy preparatory steps. We present a molecular diagnostic …
settings is a challenge due to lengthy preparatory steps. We present a molecular diagnostic …
Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes
We report on single-molecule nanopore sensing combined with position-encoded DNA
molecular probes, with chemistry tuned to simultaneously identify various antigen proteins …
molecular probes, with chemistry tuned to simultaneously identify various antigen proteins …
Multiplexed discrimination of SARS-CoV-2 variants via plasmonic-enhanced fluorescence in a portable and automated device
Portable assays for the rapid identification of lineages of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) are needed to aid large-scale efforts in monitoring the …
coronavirus 2 (SARS-CoV-2) are needed to aid large-scale efforts in monitoring the …
CRISPR-based biosensors for pathogenic biosafety
H Yang, R Ledesma-Amaro, H Gao, Y Ren… - Biosensors and …, 2023 - Elsevier
Pathogenic biosafety is a worldwide concern. Tools for analyzing pathogenic biosafety, that
are precise, rapid and field-deployable, are highly demanded. Recently developed …
are precise, rapid and field-deployable, are highly demanded. Recently developed …
A programmable DNAzyme for the sensitive detection of nucleic acids
Nucleic acids in biofluids are emerging biomarkers for the molecular diagnostics of
diseases, but their clinical use has been hindered by the lack of sensitive detection assays …
diseases, but their clinical use has been hindered by the lack of sensitive detection assays …
CRISPR‐Mediated Profiling of Viral RNA at Single‐Nucleotide Resolution
D Chen, W Huang, Y Zhang, B Chen… - Angewandte Chemie …, 2023 - Wiley Online Library
Mass pathogen screening is critical to preventing the outbreaks and spread of infectious
diseases. The large‐scale epidemic of COVID‐19 and the rapid mutation of the severe acute …
diseases. The large‐scale epidemic of COVID‐19 and the rapid mutation of the severe acute …