Single molecule detection; from microscopy to sensors

N Chauhan, K Saxena, U Jain - International Journal of Biological …, 2022 - Elsevier
Single molecule detection is necessary to find out physical, chemical properties and their
mechanism involved in the normal functioning of body cells. In this way, they can provide a …

Instrumentational implementation for parallelized nanopore electrochemical measurements

J Wang, YL Ying, CB Zhong, LM Zhang, F Yan… - Analyst, 2021 - pubs.rsc.org
Nanopore electrochemistry, as one of the promising tools for single molecule sensing, has
proved its capability in DNA sequencing and protein analysis. To achieve a high resolution …

Single-molecule and particle detection on true portable microscopy platforms

L Skolrood, Y Wang, S Zhang, Q Wei - Sensors and Actuators Reports, 2022 - Elsevier
Point-of-care technologies (POCT) that enable early disease detection and therapeutic
monitoring are crucial for the next generation of diagnostics and personalized medicine …

Nanopore Deciphering Single Digital Polymers Towards High‐Density Data Storage

ZL Hu, YH Liu, KL **n, RJ Yu… - … –A European Journal, 2023 - Wiley Online Library
Sequence‐defined polymer is one of the most promising alternative media for high‐density
data storage. It could be used to alleviate the problem of insufficient storage capacity of …

A nanopore-based label-free CRISPR/Cas12a system for portable and ultrasensitive detection of zearalenone

Z Pei, Z Su, J Chen, W Li, D Wu, L Li, Y Wu, G Li - Analytica Chimica Acta, 2024 - Elsevier
Background Food safety has become a serious global concern. Therefore, there is a need
for effective detection technologies in this field. Currently, the development of effective on …

From Molecules to Classrooms: A Comprehensive Guide to Single-Molecule Localization Microscopy

G Yan, Y Zhang, A Allamprese, KN Brooks… - Journal of Chemical …, 2024 - ACS Publications
Single-molecule localization microscopy (SMLM) has revolutionized our ability to visualize
cellular structures, offering unprecedented detail. However, the intricate biophysical …

An Enzyme Kinetics-Based Laboratory Module Aimed at Introducing Undergraduates to High-Throughput Drug Screening

X He, Y Huang, Z Xu, X Liu, Z Xu, L Ma… - Journal of Chemical …, 2023 - ACS Publications
Enzymes provide attractive targets for drug development. Quantitative analysis of enzyme
reactions can lead to rational drug discovery. For undergraduates majoring in biochemistry …

Nanotechnology and Education: Preparing the Next Generation of Future Leaders

B Tawiah, RK Seidu, GK Fobiri, CA Chichi - Nanotechnology in Societal …, 2024 - Springer
Nanotechnology, the science and engineering of manipulating matter at the nanoscale level,
has emerged as a transformative field with vast potential across various industries. As …

A two-step calibration method for evaluation high bandwidth electrochemical instrument

LL Zhang, CB Zhong, JG Li, HY Niu, YL Ying… - Journal of …, 2022 - Elsevier
Single-entity electrochemistry allows the ultrasensitive detection of individual entities by
incorporating high bandwidth electrochemical instruments. However, differences among …

Customized low-cost high-throughput amplifier for electro-fluidic detection of cell volume changes in point-of-care applications

S Kaushik, P Selvanathan, GV Soni - Plos one, 2022 - journals.plos.org
Physical parameters of the pathogenic cells, like its volume, shape, and stiffness, are
important biomarkers for diseases, chemical changes within the cell, and overall cell health …