Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative
G-quadruplexes (G4s) are important therapeutic and photopharmacological targets in
cancer research. Small-molecule ligands targeting G4s offer a promising strategy to block …
cancer research. Small-molecule ligands targeting G4s offer a promising strategy to block …
A novel platinum (ii) complex with a berberine derivative as a potential antitumor agent targeting G-quadruplex DNA
SL Zhang, H Fu, Y Ma, Q Lin, Y Xu, Q Yang… - Organic & …, 2025 - pubs.rsc.org
G-quadruplexes are considered attractive targets for various human diseases, including
cancer therapy, owing to their potential therapeutic applications. Understanding the …
cancer therapy, owing to their potential therapeutic applications. Understanding the …
Rewired Metabolism Caused by the Oncogenic Deregulation of MYC as an Attractive Therapeutic Target in Cancers
MYC is one of the most deregulated oncogenes on multiple levels in cancer. As a node
transcription factor, MYC plays a diverse regulatory role in many cellular processes …
transcription factor, MYC plays a diverse regulatory role in many cellular processes …
Reprograming cancer cells by a BODIPY G-quadruplex stabiliser
A Baser, B Basar, HB Dogan, G Sener… - Chemical …, 2023 - pubs.rsc.org
A cationic BODIPY-based G-quadruplex-selective stabiliser is developed and shown to
decrease cancer cell migration-invasion up to 90%. The expression of critical genes (HIF1α …
decrease cancer cell migration-invasion up to 90%. The expression of critical genes (HIF1α …