Marek's disease in chickens: a review with focus on immunology

N Boodhoo, A Gurung, S Sharif, S Behboudi - Veterinary research, 2016 - Springer
Abstract Marek's disease (MD), caused by Marek's disease virus (MDV), is a commercially
important neoplastic disease of poultry which is only controlled by mass vaccination …

[PDF][PDF] A brief history of vaccines and vaccination

M Lombard, PP Pastoret, AM Moulin - Revue Scientifique et …, 2007 - researchgate.net
Human vaccinology, with its primary focus on the individual, seems far removed from
veterinary medicine, with its concern for the health of the herd. Yet several episodes in the …

[HTML][HTML] Imperfect vaccination can enhance the transmission of highly virulent pathogens

AF Read, SJ Baigent, C Powers, LB Kgosana… - PLoS …, 2015 - journals.plos.org
Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom
is that natural selection will remove highly lethal pathogens if host death greatly reduces …

Latest insights into Marek's disease virus pathogenesis and tumorigenesis

LD Bertzbach, AM Conradie, Y You, BB Kaufer - Cancers, 2020 - mdpi.com
Marek's disease virus (MDV) infects chickens and causes one of the most frequent cancers
in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a …

Classification of Marek's disease viruses according to pathotype: philosophy and methodology

RL Witter, BW Calnek, C Buscaglia, IM Gimeno… - Avian …, 2005 - Taylor & Francis
The concept of pathotype in Marek's disease (MD) probably dates from the recognition of a
more virulent form of the disease in the late 1950s (Benton & Cover, Citation 1957) …

Evolution of Marek's disease–a paradigm for incessant race between the pathogen and the host

V Nair - The Veterinary Journal, 2005 - Elsevier
Marek's disease (MD) is a highly contagious lymphoproliferative disease of poultry caused
by the oncogenic herpesvirus designated Marek's disease virus (MDV). MD has a worldwide …

Environmental epigenetics and epigenetic inheritance in domestic farm animals

RP Thompson, E Nilsson, MK Skinner - Animal Reproduction Science, 2020 - Elsevier
Epigenetics refers to molecular factors and processes around DNA that can affect genome
activity and gene expression independent of DNA sequence. Epigenetic mechanisms drive …

The long view: 40 years of Marek's disease research and Avian Pathology

PM Biggs, V Nair - Avian pathology, 2012 - Taylor & Francis
Marek's disease (MD), named after the Hungarian veterinary pathologist over 100 years
ago, is a major disease affecting poultry health worldwide. Research in the late 1960s that …

Marek's disease virus and skin interactions

M Couteaudier, C Denesvre - Veterinary research, 2014 - Springer
Marek's disease virus (MDV) is a highly contagious herpesvirus which induces T-cell
lymphoma in the chicken. This virus is still spreading in flocks despite forty years of …

Interaction of MEQ protein and C-terminal-binding protein is critical for induction of lymphomas by Marek's disease virus

AC Brown, SJ Baigent, LP Smith… - Proceedings of the …, 2006 - National Acad Sciences
Marek's disease virus (MDV) is an oncogenic herpesvirus that induces fatal T cell
lymphomas in chickens. With more than 20 billion doses of vaccine used annually …