Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …

Objective The task force of the International Conference of Frailty and Sarcopenia Research
(ICFSR) developed these clinical practice guidelines to overview the current evidence-base …

Introduction Frailty is one of the greatest challenges facing our aging population, as it can
lead to adverse outcomes such as institutionalization, hospitalization, and mortality …

Aging involves decline in a range of functional abilities and phenotypes, many of which are
also associated with socioeconomic status (SES). Here we assessed whether lower SES is …

Introduction. Although frailty is common among community-dwelling older adults, its
prevalence in Europe and how this varies between countries is unclear. Methods. A …

Abstract The Longitudinal Aging Study Amsterdam (LASA) is an ongoing longitudinal study
of older adults in the Netherlands, which started in 1992. LASA is focused on the …

Frailty is characterized by diminished resilience to stressor events. It is associated with
adverse future health outcomes and impedes healthy aging. The circadian system …

Background Frailty, an age-related state of reduced physiological reserve, is often
associated with lower socio-economic position (SEP). This systematic review synthesised …

By definition, aging is a natural, gradual and continuous process. On the other hand, frailty
reflects the increase in vulnerability to stressors and shortens the time without disease …