Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for their anti-
inflammatory, antipyretic, and analgesic properties. However, their use is often associated …

Biosynthesis of zinc oxide nanoparticles (ZnO-NPs) was achieved by utilizing the reducing
and cap** potential of leaf, stem and callus aqueous extracts of Mussaenda frondosa. The …

Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Food components have long been recognized to play a fundamental role in the growth and
development of the human body, conferring protective functionalities against foreign matter …

Acute and chronic pain complaints, although common, are generally poorly served by
existing therapies. This unmet clinical need reflects a failure to develop novel classes of …

Background The analgesic efficacy and adverse effects of a single perioperative dose of
dexamethasone are unclear. We performed a systematic review to evaluate the impact of a …

Aim The aim was to investigate associations between drugs with anticholinergic effects
(DACEs) and cognitive impairment, falls and all‐cause mortality in older adults. Methods A …

In a subgroup of TOPCAT participants assigned to spironolactone, the spironolactone
metabolite canrenone was measured to assess adherence. Canrenone levels were …

Historically, most patients who required parenteral anticoagulation received heparin,
whereas those patients requiring oral anticoagulation received warfarin. Due to the narrow …