Platelets rapidly undergo responsive transitions in form and function to repair vascular
endothelium and mediate hemostasis. In contrast, heterogeneous platelet subpopulations …

Biological applications of microfluidics technology is beginning to expand beyond the
original focus of diagnostics, analytics and organ-on-chip devices. There is a growing …

Treating peripheral nerve injury faces major challenges and may benefit from bioactive
scaffolds due to the limited autograft resources. Graphene oxide (GO) has emerged as a …

Ex vivo production of human platelets has been pursued as an alternative measure to
resolve limitations in the supply and safety of current platelet transfusion products. To this …

The main function of blood platelets is to ensure hemostasis and prevent hemorrhages. The
1011 platelets needed daily are produced in a well-orchestrated process. However, this …

There is heritability to interindividual variation in platelet count, and better understanding of
the regulating genetic factors may provide insights for thrombopoiesis. MicroRNAs (miRs) …

Platelets play crucial roles in hemostasis, thrombosis, and immunity, but our understanding
of their complex biogenesis (thrombopoiesis) is currently incomplete. Deeper insight into the …

The severely decreased platelet counts (10–30. 103 platelets/μL) frequently observed in
patients undergoing chemotherapy, radiation treatment, or organ transplantation are …

Since the dawn of medicine, scientists have carefully observed, modeled and interpreted the
human body to improve healthcare. At the beginning there were drawings and paintings …

Platelets, derived from megakaryocytes, are anucleate cytoplasmic discs that circulate in the
blood stream and play major roles in hemostasis, inflammation, and vascular biology …