The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential …

H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …

Rationale for azithromycin in COVID-19: an overview of existing evidence

I Gyselinck, W Janssens… - BMJ Open …, 2021 - bmjopenrespres.bmj.com
Azithromycin has rapidly been adopted as a repurposed drug for the treatment of COVID-19,
despite the lack of high-quality evidence. In this review, we critically appraise the current …

miR-98 regulates TMPRSS2 expression in human endothelial cells: key implications for COVID-19

A Matarese, J Gambardella, C Sardu, G Santulli - Biomedicines, 2020 - mdpi.com
The two main co-factors needed by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) to enter human cells are angiotensin-converting enzyme 2 (ACE2) and …

Coronary microvascular dysfunction

S Godo, A Suda, J Takahashi, S Yasuda… - … , and vascular biology, 2021 - Am Heart Assoc
Over the past couple of decades, accumulating evidence has shown that structural and
functional abnormalities of coronary microvasculature are highly prevalent, associated with …

Statin use in COVID-19 hospitalized patients and outcomes: a retrospective study

H Kouhpeikar, H Khosaravizade Tabasi… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) might affect everyone, but people with
comorbidities such as hypertension and cardiovascular disease (CVD) may often have more …

Let fever do its job: the meaning of fever in the pandemic era

S Wrotek, EK LeGrand, A Dzialuk… - Evolution, medicine, and …, 2021 - academic.oup.com
Although fever is one of the main presenting symptoms of COVID-19 infection, little public
attention has been given to fever as an evolved defense. Fever, the regulated increase in …

Risk factors for severity of COVID-19 in chronic dialysis patients from a multicentre French cohort

G Lano, A Braconnier, S Bataille, G Cavaille… - Clinical kidney …, 2020 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging infectious
disease, related to severe acute respiratory syndrome coronavirus 2 infection. Few data are …

Novel benzimidazole angiotensin receptor blockers with anti-SARS-CoV-2 activity equipotent to that of nirmatrelvir: computational and enzymatic studies

H Ridgway, GJ Moore, LK Gadanec, A Zulli… - Expert Opinion on …, 2024 - Taylor & Francis
Background Hypertension worsens outcomes in SARS-CoV-2 patients. Sartans, a type of
antihypertensive angiotensin receptor blocker-(ARB), reduce COVID-19 morbidity and …

Coronavirus-associated kidney outcomes in COVID-19, SARS, and MERS: a meta-analysis and systematic review

S Zhou, J Xu, C Xue, B Yang, Z Mao, ACM Ong - Renal failure, 2021 - Taylor & Francis
Objectives A meta-analysis and systematic review was conducted on kidney-related
outcomes of three recent pandemics: SARS, MERS, and COVID-19, which were associated …

COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart

M Pesce, P Agostoni, HE Bøtker… - Cardiovascular …, 2021 - academic.oup.com
The pandemic of coronavirus disease (COVID)-19 is a global threat, causing high mortality,
especially in the elderly. The main symptoms and the primary cause of death are related to …