Conspectus Coacervates are droplets formed by liquid–liquid phase separation (LLPS) and
are often used as model protocells–primitive cell-like compartments that could have aided …

The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …

Bottom-up assembly of higher-order cytomimetic systems capable of coordinated physical
behaviours, collective chemical signalling and spatially integrated processing is a key …

Co-phase separation of RNAs and RNA-binding proteins drives the biogenesis of
ribonucleoprotein granules. RNAs can also undergo phase transitions in the absence of …

Conspectus Cells have evolved to be self-sustaining compartmentalized systems that
consist of many thousands of biomolecules and metabolites interacting in complex cycles …

Living and proliferating cells undergo repeated cycles of growth, replication and division, all
orchestrated by complex molecular networks. How a minimal cell cycle emerged and helped …

Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless
compartments in biology and may have played a role in the formation of protocells that …

Coacervation has emerged as a prevalent mechanism to compartmentalize biomolecules in
living cells. Synthetic coacervates help in understanding the assembly process and mimic …

Generally, rolling circle amplification (RCA) is based on an enzyme-linked padlock
extension reaction. Herein, rapid linking that utilizes click chemistry for joining sticky ends of …

Recently, it has been demonstrated that thermoviscous flows can be used for a range of fine
micromanipulations, such as moving the cytoplasm of cells and develo** embryos …