Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …

Inflammation is a protective response of the body potentially caused by microbial, viral, or
fungal infections, tissue damage, or even autoimmune reactions. The cardinal signs of …

Raspberries (Rubus idaeus) possess a wide phenolic family profile; this serves the role of
self-protection for the plant. Interest in these compounds have significantly increased, since …

The skin, acting as the outer protection of the human body, is most vulnerable to injury.
Wound healing can often be impaired, leading to chronic, hard-to-heal wounds. For this …

Animal models of inflammatory bowel disease (IBD) are valuable tools for investigating the
factors involved in IBD pathogenesis and evaluating new therapeutic options. The dextran …

Major depressive disorder is a debilitating disorder affecting millions of people each year.
Brain-derived neurotrophic factor (BDNF) and inflammation are two prominent biologic risk …

During carcinogenesis, advanced tumors are surrounded by both stromal and immune cells,
which support tumor development. In addition, inflammation and angiogenesis are …

Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present
in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory …

Activation of the innate immune system following pattern recognition receptor binding has
emerged as one of the major pathogenic mechanisms in neurodegenerative disease …