Supercritical fluid technology: an emphasis on drug delivery and related biomedical applications
During the past few decades, supercritical fluid (SCF) has emerged as an effective
alternative for many traditional pharmaceutical manufacturing processes. Operating active …
alternative for many traditional pharmaceutical manufacturing processes. Operating active …
Advancement in solubilization approaches: a step towards bioavailability enhancement of poorly soluble drugs
L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …
is currently a major hurdle in bringing new drug molecules to the market. According to some …
Enhancing the solubility and bioavailability of poorly water-soluble drugs using supercritical antisolvent (SAS) process
Poor water solubility and poor bioavailability are problems with many pharmaceuticals.
Increasing surface area by micronization is an effective strategy to overcome these …
Increasing surface area by micronization is an effective strategy to overcome these …
Supercritical fluid (SCF)-assisted fabrication of carrier-free drugs: an eco-friendly welcome to active pharmaceutical ingredients (APIs)
Despite the success in develo** various pharmaceutical formulations, most of the active
pharmaceutical ingredients (APIs)/drugs, according to the Biopharmaceutics Classification …
pharmaceutical ingredients (APIs)/drugs, according to the Biopharmaceutics Classification …
Preparation, characterization and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process
In this work, amorphous atorvastatin calcium nanoparticles were successfully prepared
using the supercritical antisolvent (SAS) process. The effect of process variables on particle …
using the supercritical antisolvent (SAS) process. The effect of process variables on particle …
Polymorphism and crystallization of active pharmaceutical ingredients (APIs)
Active pharmaceutical ingredients (APIs), frequently delivered to the patient in the solid-state
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
Polymorphism and solvatomorphism 2010
HG Brittain - Journal of pharmaceutical sciences, 2012 - Elsevier
Papers and patents that deal with polymorphism (crystal systems for which a substance can
exist in structures defined by different unit cells and where each of the forms has the same …
exist in structures defined by different unit cells and where each of the forms has the same …
Augmented control of drug-resistant Candida spp. via fluconazole loading into fungal chitosan nanoparticles
Fungal chitosan (ACT) extraction from Amylomyces rouxii, its transforming into nano-form,
loading with fluconazole (Flu) and evaluation of synthesized nanoconjugates against drug …
loading with fluconazole (Flu) and evaluation of synthesized nanoconjugates against drug …
Mechanisms controlling supercritical antisolvent precipitate morphology
Supercritical antisolvent precipitation (SAS) has been successfully used to micronize several
kinds of materials. A great variety of morphologies, such as nanoparticles with mean …
kinds of materials. A great variety of morphologies, such as nanoparticles with mean …
[HTML][HTML] Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques
Poor bioavailability and aqueous solubility represent a major constraint during the
development of new API molecules and can influence the impact of new medicines or halt …
development of new API molecules and can influence the impact of new medicines or halt …