Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa
isolates are frequent causes of serious nosocomial infections that may compromise the …
isolates are frequent causes of serious nosocomial infections that may compromise the …
[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …
spread of genes coding for resistance determinants among bacteria challenges the use of …
Multidrug efflux pumps: structure, function and regulation
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …
throughout the world and threaten to become untreatable. The origins of resistance are …
The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies
P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …
Review on the antibacterial mechanism of plant‐derived compounds against multidrug‐resistant bacteria (MDR)
Microbial resistance has progressed rapidly and is becoming the leading cause of death
globally. The spread of antibiotic‐resistant microorganisms has been a significant threat to …
globally. The spread of antibiotic‐resistant microorganisms has been a significant threat to …
Bacterial multidrug efflux pumps at the frontline of antimicrobial resistance: an overview
L Huang, C Wu, H Gao, C Xu, M Dai, L Huang, H Hao… - Antibiotics, 2022 - mdpi.com
Multidrug efflux pumps function at the frontline to protect bacteria against antimicrobials by
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
decreasing the intracellular concentration of drugs. This protective barrier consists of a …
Pseudomonas aeruginosa reference strains PAO1 and PA14: A genomic, phenotypic, and therapeutic review
A Grace, R Sahu, DR Owen, VA Dennis - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa is a ubiquitous, motile, gram-negative bacterium that has been
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …
recently identified as a multi-drug resistant pathogen in critical need of novel therapeutics. Of …
Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria
Researchers, clinicians and governments all recognize antimicrobial resistance as a serious
and growing threat worldwide. New antimicrobials are urgently needed, especially for …
and growing threat worldwide. New antimicrobials are urgently needed, especially for …