Host recovery from respiratory viral infection

X Wei, H Narasimhan, B Zhu… - Annual Review of …, 2023 - annualreviews.org
Emerging and re-emerging respiratory viral infections pose a tremendous threat to human
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …

Regulatory T cell and macrophage crosstalk in acute lung injury: future perspectives

T Guan, X Zhou, W Zhou, H Lin - Cell Death Discovery, 2023 - nature.com
Acute lung injury (ALI) describes the injury to endothelial cells in the lungs and associated
vessels due to various factors. Furthermore, ALI accompanied by inflammation and …

Animal models in SARS-CoV-2 research

H Chu, JFW Chan, KY Yuen - Nature methods, 2022 - nature.com
Animal models in SARS-CoV-2 research | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Profound Treg perturbations correlate with COVID-19 severity

S Galván-Peña, J Leon, K Chowdhary… - Proceedings of the …, 2021 - pnas.org
The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from
poorly understood immunological dysfunction. We hypothesized that perturbations in …

Treg–tissue cell interactions in repair and regeneration

LF Loffredo, TM Savage, OR Ringham… - Journal of Experimental …, 2024 - rupress.org
Regulatory T (Treg) cells are classically known for their critical immunosuppressive functions
that support peripheral tolerance. More recent work has demonstrated that Treg cells …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

[HTML][HTML] Differential roles of regulatory T cells in acute respiratory infections

M Jovisic, N Mambetsariev, BD Singer… - The Journal of Clinical …, 2023 - jci.org
JCI - Differential roles of regulatory T cells in acute respiratory infections Go to JCI Insight About
Editors Consulting Editors For authors Publication ethics Publication alerts by email Advertising …

Regulatory T cells in peripheral tissue tolerance and diseases

N Cheru, DA Hafler, TS Sumida - Frontiers in Immunology, 2023 - frontiersin.org
Maintenance of peripheral tolerance by CD4+ Foxp3+ regulatory T cells (Tregs) is essential
for regulating autoreactive T cells. The loss of function of Foxp3 leads to autoimmune …

Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …