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Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …
and adverse health outcomes, which have been received substantial and increasing …
Assessing the ecological risks of per‐and polyfluoroalkyl substances: Current state‐of‐the science and a proposed path forward
Per‐and poly‐fluoroalkyl substances (PFAS) encompass a large, heterogenous group of
chemicals of potential concern to human health and the environment. Based on information …
chemicals of potential concern to human health and the environment. Based on information …
[HTML][HTML] (Eco) toxicological tests for assessing impacts of chemical stress to aquatic ecosystems: facts, challenges, and future
Monitoring of chemicals in the aquatic environment by chemical analysis alone cannot
completely assess and predict the effects of chemicals on aquatic species and ecosystems …
completely assess and predict the effects of chemicals on aquatic species and ecosystems …
Species sensitivity to toxic substances: Evolution, ecology and applications
Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …
High‐throughput screening and environmental risk assessment: State of the science and emerging applications
ABSTRACT In 2007 the United States National Research Council (NRC) published a vision
for toxicity testing in the 21st century that emphasized the use of in vitro high‐throughput …
for toxicity testing in the 21st century that emphasized the use of in vitro high‐throughput …
Potential toxicity of complex mixtures in surface waters from a nationwide survey of United States streams: Identifying in vitro bioactivities and causative chemicals
While chemical analysis of contaminant mixtures remains an essential component of
environmental monitoring, bioactivity-based assessments using in vitro systems increasingly …
environmental monitoring, bioactivity-based assessments using in vitro systems increasingly …
Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption
A growing number of environmental pollutants are known to adversely affect the thyroid
hormone system, and major gaps have been identified in the tools available for the …
hormone system, and major gaps have been identified in the tools available for the …
Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption
Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …
AOP report: Thyroperoxidase inhibition leading to altered visual function in fish via altered retinal layer structure
Thyroid hormones (THs) are involved in the regulation of many important physiological and
developmental processes, including vertebrate eye development. Thyroid hormone system …
developmental processes, including vertebrate eye development. Thyroid hormone system …
Three perspectives on the prediction of chemical effects in ecosystems
A Schneeweiss, NPD Juvigny‐Khenafou… - Global Change …, 2023 - Wiley Online Library
The increasing production, use and emission of synthetic chemicals into the environment
represents a major driver of global change. The large number of synthetic chemicals, limited …
represents a major driver of global change. The large number of synthetic chemicals, limited …