Low-dose aspirin and the risk of stroke and intracerebral bleeding in healthy older people: secondary analysis of a randomized clinical trial
GC Cloud, JD Williamson, C Tran, CB Eaton… - JAMA Network …, 2023 - jamanetwork.com
Importance Low-dose aspirin has been widely used for primary and secondary prevention of
stroke. The balance between potential reduction of ischemic stroke events and increased …
stroke. The balance between potential reduction of ischemic stroke events and increased …
[HTML][HTML] Delphi initiative for early-onset colorectal cancer (DIRECt) international management guidelines
GM Cavestro, A Mannucci, F Balaguer… - Clinical …, 2023 - Elsevier
Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …
according to guidelines that are not age-specific. A multidisciplinary international group …
Aspirin for secondary prevention of cardiovascular disease in 51 low-, middle-, and high-income countries
Importance Aspirin is an effective and low-cost option for reducing atherosclerotic
cardiovascular disease (CVD) events and improving mortality rates among individuals with …
cardiovascular disease (CVD) events and improving mortality rates among individuals with …
Health characteristics and aspirin use in participants at the baseline of the aspirin in reducing events in the elderly–eXTension (ASPREE-XT) observational study
Background Aspirin as a primary preventative in healthy older adults did not prolong
disability-free survival in the ASPREE randomized trial. Observational studies following …
disability-free survival in the ASPREE randomized trial. Observational studies following …
Effect of low-dose aspirin versus placebo on incidence of anemia in the elderly: a secondary analysis of the aspirin in reducing events in the elderly trial
Background: Daily low-dose aspirin increases major bleeding; however, few studies have
investigated its effect on iron deficiency and anemia. Objective: To investigate the effect of …
investigated its effect on iron deficiency and anemia. Objective: To investigate the effect of …
Short-and long-term impact of aspirin cessation in older adults: a target trial emulation
Background The net benefit of aspirin cessation in older adults remains uncertain. This study
aimed to use observational data to emulate a randomized trial of aspirin cessation versus …
aimed to use observational data to emulate a randomized trial of aspirin cessation versus …
Association of aspirin use with risk of intracerebral hemorrhage in patients without history of stroke or transient ischemic attack in the UK Biobank
Z Wang, X Liu, S Zhang, X Hu… - International Journal of …, 2025 - journals.sagepub.com
Background: The association between aspirin use and the risk of intracerebral hemorrhage
(ICH) among individuals without previous stroke events is inconclusive. Aim: We …
(ICH) among individuals without previous stroke events is inconclusive. Aim: We …
Risk of atherosclerotic cardiovascular disease hospitalizations after chronic obstructive pulmonary disease hospitalization among older adults
CL Mosher, OL Osazuwa-Peters… - Annals of the …, 2024 - atsjournals.org
Rationale: Meta-analyses have suggested the risk of cardiovascular disease (CVD) events
is significantly higher after a chronic obstructive pulmonary disease (COPD) exacerbation …
is significantly higher after a chronic obstructive pulmonary disease (COPD) exacerbation …
Temporal trends in low-dose aspirin therapy for primary prevention of cardiovascular disease in European adults with and without diabetes
AMD Kristensen, M Pareek… - European Journal of …, 2023 - academic.oup.com
Aims Aspirin therapy for primary prevention of cardiovascular disease (CVD) is
controversial, and guideline recommendations have changed throughout the last decades …
controversial, and guideline recommendations have changed throughout the last decades …
[HTML][HTML] Impact of aspirin on pancreatic cancer in the elderly: analysis of socioeconomic status and outcomes of national matched cohorts
T Suenghataiphorn, T Lohawatcharagul… - Annals of …, 2024 - pmc.ncbi.nlm.nih.gov
Background Pancreatic cancer is a neoplastic condition with a high disease burden. It is
projected to be the second most common cause of cancer-related deaths by 2030. However …
projected to be the second most common cause of cancer-related deaths by 2030. However …