Vascular inflammation and oxidative stress: major triggers for cardiovascular disease
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …
Advanced glycation end products (AGEs): biochemistry, signaling, analytical methods, and epigenetic effects
The advanced glycation end products (AGEs) are organic molecules formed in any living
organisms with a great variety of structural and functional properties. They are considered …
organisms with a great variety of structural and functional properties. They are considered …
The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD
S Datta, M Cano, K Ebrahimi, L Wang… - Progress in retinal and …, 2017 - Elsevier
The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that
interacts with photoreceptors on its apical side and with Bruch's membrane and the …
interacts with photoreceptors on its apical side and with Bruch's membrane and the …
Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus
N Katakami - Journal of atherosclerosis and thrombosis, 2018 - jstage.jst.go.jp
Diabetic macroangiopathy, atherosclerosis secondary to diabetes mellitus (DM), causes
cerebro-cardiovascular diseases, which are major causes of death in patients with DM and …
cerebro-cardiovascular diseases, which are major causes of death in patients with DM and …
Advanced glycation end products and diabetes mellitus: mechanisms and perspectives
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …
The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review
SL Fishman, H Sonmez, C Basman, V Singh… - Molecular …, 2018 - Springer
Background Traditional risk factors are insufficient to explain all cases of coronary artery
disease (CAD) in patients with diabetes mellitus (DM). Advanced glycation end-products …
disease (CAD) in patients with diabetes mellitus (DM). Advanced glycation end-products …
Pathophysiology of RAGE in inflammatory diseases
H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
Methylglyoxal and its adducts: Induction, repair, and association with disease
SWT Lai, EDJ Lopez Gonzalez, T Zoukari… - Chemical research in …, 2022 - ACS Publications
Metabolism is an essential part of life that provides energy for cell growth. During metabolic
flux, reactive electrophiles are produced that covalently modify macromolecules, leading to …
flux, reactive electrophiles are produced that covalently modify macromolecules, leading to …
[PDF][PDF] Advanced glycation end products and diabetic complications
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent
adducts with the plasma proteins through a non-enzymatic process known as glycation …
adducts with the plasma proteins through a non-enzymatic process known as glycation …
Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …