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Epithelial–mesenchymal transition in tissue repair and degeneration
Epithelial–mesenchymal transitions (EMTs) are the epitome of cell plasticity in embryonic
development and cancer; during EMT, epithelial cells undergo dramatic phenotypic changes …
development and cancer; during EMT, epithelial cells undergo dramatic phenotypic changes …
Identification, discrimination and heterogeneity of fibroblasts
Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix
components during tissue development, homeostasis, repair and disease. Despite this …
components during tissue development, homeostasis, repair and disease. Despite this …
Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration
The molecular mechanism underlying brain regeneration in vertebrates remains elusive. We
performed spatial enhanced resolution omics sequencing (Stereo-seq) to capture spatially …
performed spatial enhanced resolution omics sequencing (Stereo-seq) to capture spatially …
Chemical reprogramming of human somatic cells to pluripotent stem cells
Cellular reprogramming can manipulate the identity of cells to generate the desired cell
types,–. The use of cell intrinsic components, including oocyte cytoplasm and transcription …
types,–. The use of cell intrinsic components, including oocyte cytoplasm and transcription …
Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges
W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …
Metabolic orchestration of the wound healing response
Wound healing requires cooperation between different cell types, among which
macrophages play a central role. In particular, inflammatory macrophages are engaged in …
macrophages play a central role. In particular, inflammatory macrophages are engaged in …
The cellular and physiological basis for lung repair and regeneration: past, present, and future
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …
Chemical reprogramming for cell fate manipulation: methods, applications, and perspectives
J Wang, S Sun, H Deng - Cell Stem Cell, 2023 - cell.com
Chemical reprogramming offers an unprecedented opportunity to control somatic cell fate
and generate desired cell types including pluripotent stem cells for applications in …
and generate desired cell types including pluripotent stem cells for applications in …
Dissecting cellular crosstalk by sequencing physically interacting cells
Crosstalk between neighboring cells underlies many biological processes, including cell
signaling, proliferation and differentiation. Current single-cell genomic technologies profile …
signaling, proliferation and differentiation. Current single-cell genomic technologies profile …
A population of stem cells with strong regenerative potential discovered in deer antlers
The annual regrowth of deer antlers provides a valuable model for studying organ
regeneration in mammals. We describe a single-cell atlas of antler regrowth. The earliest …
regeneration in mammals. We describe a single-cell atlas of antler regrowth. The earliest …