Shared and distinct functions of type I and type III interferons

HM Lazear, JW Schoggins, MS Diamond - Immunity, 2019 - cell.com
Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance

NA Terrault, ASF Lok, BJ McMahon, KM Chang… - …, 2018 - Wiley Online Library
This AASLD 2018 Hepatitis B Guidance is intended to complement the AASLD 2016
Practice Guidelines for Treatment of Chronic Hepatitis B (1) and update the previous …

Chronic hepatitis B infection: a review

LSY Tang, E Covert, E Wilson, S Kottilil - Jama, 2018 - jamanetwork.com
Importance More than 240 million individuals worldwide are infected with chronic hepatitis B
virus (HBV). Among individuals with chronic HBV infection who are untreated, 15% to 40 …

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

SK Sarin, M Kumar, GK Lau, Z Abbas, HLY Chan… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

Getting to HBV cure: The promising paths forward

S Fung, HSJ Choi, A Gehring, HLA Janssen - Hepatology, 2022 - Wiley Online Library
Chronic HBV infection is a global public health burden estimated to impact nearly 300
million persons worldwide. Despite the advent of potent antiviral agents that effectively …

[PDF][PDF] A ASLD guidelines for treatment of chronic hepatitis B

NA Terrault, NH Bzowej, KM Chang, JP Hwang… - …, 2016 - Wiley Online Library
A<fc>ASLD</fc> guidelines for treatment of chronic hepatitis <fc>B</fc> Page 1 PRACTICE
GUIDELINE AASLD Guidelines for Treatment of Chronic Hepatitis B Norah A. Terrault,1 Natalie …

[HTML][HTML] Probability of HBsAg loss after nucleo (s) tide analogue withdrawal depends on HBV genotype and viral antigen levels

MJ Sonneveld, SM Chiu, JY Park, SM Brakenhoff… - Journal of …, 2022 - Elsevier
Background & Aims Nucleo (s) tide analogue (NUC) withdrawal may result in HBsAg
clearance in a subset of patients. However, predictors of HBsAg loss after NUC withdrawal …

Hepatitis B virus infection

C Trépo, HLY Chan, A Lok - The Lancet, 2014 - thelancet.com
Hepatitis B virus infection is a major public health problem worldwide; roughly 30% of the
world's population show serological evidence of current or past infection. Hepatitis B virus is …

Safety and efficacy of 48 weeks REP 2139 or REP 2165, tenofovir disoproxil, and pegylated interferon alfa-2a in patients with chronic HBV infection naïve to nucleos (t …

M Bazinet, V Pântea, G Placinta, I Moscalu… - Gastroenterology, 2020 - Elsevier
Background & Aims Nucleic acid polymers (NAPs) inhibit assembly and secretion of
hepatitis B virus (HBV) subviral particles. We performed an open-label, phase 2 study of the …

The role of quantitative hepatitis B surface antigen revisited

M Cornberg, VWS Wong, S Locarnini, M Brunetto… - Journal of …, 2017 - Elsevier
In the past 10 years, there has been a lot of enthusiasm surrounding the use of serum
hepatitis B surface antigen (HBsAg) quantification to predict disease activity and monitor …