The intriguing structural diversity in folded topologies available to guanine-rich nucleic acid
repeat sequences have made four-stranded G-quadruplex structures the focus of both basic …

In human cells, nucleic acids adopt several non-canonical structures that regulate key
cellular processes. Among them, G-quadruplexes (G4s) are stable structures that form in …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

In this review, we give an overview of recent literature on the structure and stability of
unimolecular G-rich quadruplex structures that are relevant to drug design and for in vivo …

G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich
DNA or RNA. The conformation and function of G-quadruplex are determined by a number …

Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …

In contrast to B-DNA that has a right-handed double helical structure with Watson–Crick
base pairing under the ordinary physiological conditions, repetitive DNA sequences under …

G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …

Abstract G-quadruplex (G4) structures have been predicted in the genomes of many
organisms and proven to play regulatory roles in diverse cellular activities. However, there is …

Potassium is especially crucial in modulating the activity of muscles and nerves whose cells
have specialized ion channels for transporting potassium. Normal body function extremely …