In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to loss of
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …

Mitochondria contribute to shape intraneuronal Ca2+ signals. Excessive Ca2+ taken up by
mitochondria could lead to cell death. Amyloid beta (Aβ) causes cytosolic Ca2+ overload …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …

The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

The coexistence of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the neocortex is
linked to neural system failure and cognitive decline in Alzheimer's disease. However, the …

The function of neural circuits and networks can be controlled, in part, by modulating the
synchrony of their components' activities. Network hypersynchrony and altered oscillatory …

Alzheimer's disease (AD) is the most prevalent form of dementia which affects people older
than 60 years of age. In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the …

An essential feature of Alzheimer's disease (AD) is the accumulation of amyloid-β (Aβ)
peptides in the brain, many years to decades before the onset of overt cognitive symptoms …