Diagnosis for latent tuberculosis infection: new alternatives
C Carranza, S Pedraza-Sanchez… - Frontiers in …, 2020 - frontiersin.org
Latent tuberculosis infection (LTBI) is a subclinical mycobacterial infection defined on the
basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) …
basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) …
Differential diagnosis of latent tuberculosis infection and active tuberculosis: a key to a successful tuberculosis control strategy
W Gong, X Wu - Frontiers in microbiology, 2021 - frontiersin.org
As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …
Impact of the COVID-19 pandemic on tuberculosis control: an overview
Throughout history, pandemics of viral infections such as HIV, Ebola and Influenza have
disrupted health care systems, including the prevention and control of endemic diseases …
disrupted health care systems, including the prevention and control of endemic diseases …
Macrophage: a cell with many faces and functions in tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …
primarily infects the macrophages. Nearly a quarter of the world's population is infected …
Latent tuberculosis: two centuries of confusion
The current dogma is that 2 billion individuals, making up a quarter of the world's population,
are latently infected with Mycobacterium tuberculosis (1–4). It is thought that latent …
are latently infected with Mycobacterium tuberculosis (1–4). It is thought that latent …
The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot
Multidrug-resistant tuberculosis (MDR-TB) is among the most frequent causes of death due
to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical …
to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical …
Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis
MG Moule, JD Cirillo - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections
worldwide occur at extrapulmonary sites causing additional complications for diagnosis and …
worldwide occur at extrapulmonary sites causing additional complications for diagnosis and …
The tuberculous granuloma and preexisting immunity
Pulmonary granulomas are widely considered the epicenters of the immune response to
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal …
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal …
[HTML][HTML] Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling
Background To end the global tuberculosis epidemic, latent tuberculosis infection needs to
be addressed. All standard treatments for latent tuberculosis contain drugs to which …
be addressed. All standard treatments for latent tuberculosis contain drugs to which …
Are we underestimating the annual risk of infection with Mycobacterium tuberculosis in high-burden settings?
The annual risk of infection with Mycobacterium tuberculosis determines a population's
exposure level and thus the fraction of incident tuberculosis resulting from recent infection …
exposure level and thus the fraction of incident tuberculosis resulting from recent infection …