Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

Stretchable hybrid devices have enabled high-fidelity implantable,–and on-skin,–monitoring
of physiological signals. These devices typically contain soft modules that match the …

Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …

Cervical spinal cord injury (SCI) leads to permanent impairment of arm and hand functions.
Here we conducted a prospective, single-arm, multicenter, open-label, non-significant risk …

To construct tissue-like prosthetic materials, soft electroactive hydrogels are the best
candidate owing to their physiological mechanical modulus, low electrical resistance and …

Brain–machine interfaces typically rely on electrophysiological signals to interpret and
transmit neurological information. In biological systems, however, neurotransmitters are …

Here, we introduce the Tabulae Paralytica—a compilation of four atlases of spinal cord
injury (SCI) comprising a single-nucleus transcriptome atlas of half a million cells, a …

Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

A spinal cord injury interrupts pathways from the brain and brainstem that project to the
lumbar spinal cord, leading to paralysis. Here we show that spatiotemporal epidural …