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The mercurial nature of neutrophils: still an enigma in ARDS?
AE Williams, RC Chambers - American Journal of …, 2014 - journals.physiology.org
The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …
from direct and indirect insults to the lung. It is characterized by disruption of the endothelial …
Interleukin 8 and acute lung injury
TC Allen, A Kurdowska - Archives of Pathology and …, 2014 - meridian.allenpress.com
Acute lung injury is a complex clinical syndrome involving acute inflammation, microvascular
damage, and increased pulmonary vascular and epithelial permeability, frequently resulting …
damage, and increased pulmonary vascular and epithelial permeability, frequently resulting …
MicroRNA-127 inhibits lung inflammation by targeting IgG Fcγ receptor I
The molecular mechanisms of acute lung injury are incompletely understood. MicroRNAs
(miRNAs) are crucial biological regulators that act by suppressing their target genes and are …
(miRNAs) are crucial biological regulators that act by suppressing their target genes and are …
The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production
We have previously demonstrated that the addition of immune complexes (IC) to stimulated
macrophages could profoundly influence cytokine production. In the present work we sought …
macrophages could profoundly influence cytokine production. In the present work we sought …
[HTML][HTML] Dissecting the novel mechanism of reduning injection in treating Coronavirus Disease 2019 (COVID-19) based on network pharmacology and experimental …
S Jia, H Luo, X Liu, X Fan, Z Huang, S Lu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Reduning injection (RDNI) is a patented Traditional
Chinese medicine that contains three Chinese herbal medicines, respectively are the dry …
Chinese medicine that contains three Chinese herbal medicines, respectively are the dry …
[HTML][HTML] Anti-cytokine autoantibodies in systemic lupus erythematosus
HS Howe, BPL Leung - Cells, 2019 - mdpi.com
Cytokine dysregulation is characteristic of systemic lupus erythematosus (SLE), a systemic
autoimmune disease of considerable heterogeneity. Insights gained about the cytokine …
autoimmune disease of considerable heterogeneity. Insights gained about the cytokine …
Metalloproteinase-9 contributes to endothelial dysfunction in atherosclerosis via protease activated receptor-1
JM Florence, A Krupa, LM Booshehri, TC Allen… - PLoS …, 2017 - journals.plos.org
The atherosclerotic process begins when vascular endothelial cells undergo pro-
inflammatory changes such as aberrant activation to dysfunctional phenotypes and …
inflammatory changes such as aberrant activation to dysfunctional phenotypes and …
Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury
A Krupa, M Fol, M Rahman, KY Stokes… - … of Physiology-Lung …, 2014 - journals.physiology.org
Previous observations made by our laboratory indicate that Bruton's tyrosine kinase (Btk)
may play an important role in the pathophysiology of local inflammation in acute lung injury …
may play an important role in the pathophysiology of local inflammation in acute lung injury …
Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor–4 receptor crosstalk in human neutrophils
Previous observations by our laboratory indicate that the presence of anti–IL-8 autoantibody:
IL-8 immune complexes in lung fluids from patients with acute lung injury/acute respiratory …
IL-8 immune complexes in lung fluids from patients with acute lung injury/acute respiratory …
Growth factors and cytokines in acute lung injury
JC Deng, TJ Standiford - Comprehensive Physiology, 2010 - Wiley Online Library
Cytokines and growth factors play an integral role in the maintenance of immune
homeostasis, the generation of protective immunity, and lung reparative processes …
homeostasis, the generation of protective immunity, and lung reparative processes …