Interventions to improve the appropriate use of polypharmacy for older people

A Rankin, CA Cadogan, SM Patterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

[HTML][HTML] Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis

AB Mekonnen, AJ McLachlan, EB Jo-anne - BMJ open, 2016 - bmjopen.bmj.com
Objectives Pharmacists play a role in providing medication reconciliation. However, data on
effectiveness on patients' clinical outcomes appear inconclusive. Thus, the aim of this study …

Reducing inappropriate polypharmacy: the process of deprescribing

IA Scott, SN Hilmer, E Reeve, K Potter… - JAMA internal …, 2015 - jamanetwork.com
Inappropriate polypharmacy, especially in older people, imposes a substantial burden of
adverse drug events, ill health, disability, hospitalization, and even death. The single most …

Adverse drug reactions in special populations–the elderly

EA Davies, MS O'mahony - British journal of clinical …, 2015 - Wiley Online Library
The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

A systematic review of the evidence for deprescribing interventions among older people living with frailty

K Ibrahim, NJ Cox, JM Stevenson, S Lim, SDS Fraser… - BMC geriatrics, 2021 - Springer
Background Older people living with frailty are often exposed to polypharmacy and potential
harm from medications. Targeted deprescribing in this population represents an important …

Predicting risk of adverse drug reactions in older adults

AH Lavan, P Gallagher - Therapeutic advances in drug …, 2016 - journals.sagepub.com
Adverse drug reactions (ADRs) are common in older adults, with falls, orthostatic
hypotension, delirium, renal failure, gastrointestinal and intracranial bleeding being amongst …

Effect of an in-hospital multifaceted clinical pharmacist intervention on the risk of readmission: a randomized clinical trial

LV Ravn-Nielsen, ML Duckert, ML Lund… - JAMA internal …, 2018 - jamanetwork.com
Importance Hospital readmissions are common among patients receiving multiple
medications, with considerable costs to the patients and society. Objective To determine …

Effectiveness of medication review: a systematic review and meta-analysis of randomized controlled trials

VJB Huiskes, DM Burger, CHM Van Den Ende… - BMC family …, 2017 - Springer
Background Medication review is often recommended to optimize medication use. In clinical
practice it is mostly operationalized as an intervention without co-interventions during a short …

Medication errors: an overview for clinicians

CM Wittich, CM Burkle, WL Lanier - Mayo Clinic Proceedings, 2014 - Elsevier
Medication error is an important cause of patient morbidity and mortality, yet it can be a
confusing and underappreciated concept. This article provides a review for practicing …

Impact of deprescribing interventions in older hospitalised patients on prescribing and clinical outcomes: a systematic review of randomised trials

J Thillainadesan, D Gnjidic, S Green, SN Hilmer - Drugs & aging, 2018 - Springer
Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …