Complex multicellular organisms require a coordinated response from multiple tissues to
maintain whole-body homeostasis in the face of energetic stressors such as fasting, cold …

Mitochondria play a central role in cellular energy metabolism, and their dysfunction is
increasingly recognized as a critical factor in the pathogenesis of diabetes-related cardiac …

Targeting metabolic vulnerability of tumor cells is a promising anticancer strategy. However,
the therapeutic efficacy of existing metabolism‐regulating agents is often compromised due …

Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase
(AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3 …

Intestinal metabolism-related diseases, such as constipation, inflammatory bowel disease,
irritable bowel syndrome, and colorectal cancer, could be associated with the dysfunction of …

Miro proteins are universally conserved mitochondrial calcium-binding GTPases that
regulate a multitude of mitochondrial processes, including transport, clearance, and lipid …

Insulin resistance is a critical pathophysiological process in the onset and advancement of
type 2 diabetes mellitus. It is well-recognized that alterations in the metabolism of lipids and …