Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Mito‐bomb: targeting mitochondria for cancer therapy
X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …
photochemical properties of transition metal complexes for diagnostic and therapeutic …
Supramolecular cancer nanotheranostics
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
Golgi apparatus-targeted aggregation-induced emission luminogens for effective cancer photodynamic therapy
M Liu, Y Chen, Y Guo, H Yuan, T Cui, S Yao… - Nature …, 2022 - nature.com
Golgi apparatus (GA) oxidative stress induced by in situ reactive oxygen species (ROS)
could severely damage the morphology and function of GA, which may open up an avenue …
could severely damage the morphology and function of GA, which may open up an avenue …
Photosensitizers for photodynamic therapy
M Lan, S Zhao, W Liu, CS Lee… - Advanced healthcare …, 2019 - Wiley Online Library
As an emerging clinical modality for cancer treatment, photodynamic therapy (PDT) takes
advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by …
advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by …
Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433
Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
Visible-light-mediated modification and manipulation of biomacromolecules
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …
have become crucial tools in chemical biology. They are extensively used not only to …
Organelle-targeted photosensitizers for precision photodynamic therapy
Subcellular organelles are the cornerstones of cells, and destroying them will cause cell
dysfunction and even death. Therefore, realizing precise organelle targeting of …
dysfunction and even death. Therefore, realizing precise organelle targeting of …
Fluorescent probes for organelle-targeted bioactive species imaging
P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …