The Ka/Ks ratio: diagnosing the form of sequence evolution
LD Hurst - TRENDS in Genetics, 2002 - cell.com
There are several different ways you could do this. There is an excellent free package for
PCs called MEGA2 that implements loads of different methods: http://www. megasoftware …
PCs called MEGA2 that implements loads of different methods: http://www. megasoftware …
The complete sequence of a human genome
Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished …
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished …
The origin and evolution of model organisms
SB Hedges - Nature Reviews Genetics, 2002 - nature.com
The phylogeny and timescale of life are becoming better understood as the analysis of
genomic data from model organisms continues to grow. As a result, discoveries are being …
genomic data from model organisms continues to grow. As a result, discoveries are being …
Synonymous mutations in representative yeast genes are mostly strongly non-neutral
Synonymous mutations in protein-coding genes do not alter protein sequences and are thus
generally presumed to be neutral or nearly neutral,,,–. Here, to experimentally verify this …
generally presumed to be neutral or nearly neutral,,,–. Here, to experimentally verify this …
Complete genomic and epigenetic maps of human centromeres
Existing human genome assemblies have almost entirely excluded repetitive sequences
within and near centromeres, limiting our understanding of their organization, evolution, and …
within and near centromeres, limiting our understanding of their organization, evolution, and …
MEGA6: molecular evolutionary genetics analysis version 6.0
K Tamura, G Stecher, D Peterson… - … biology and evolution, 2013 - academic.oup.com
We announce the release of an advanced version of the Molecular Evolutionary Genetics
Analysis (MEGA) software, which currently contains facilities for building sequence …
Analysis (MEGA) software, which currently contains facilities for building sequence …
Predicting functional effect of human missense mutations using PolyPhen‐2
I Adzhubei, DM Jordan… - Current protocols in …, 2013 - Wiley Online Library
Abstract PolyPhen‐2 (Polymorphism Phenoty** v2), available as software and via a Web
server, predicts the possible impact of amino acid substitutions on the stability and function …
server, predicts the possible impact of amino acid substitutions on the stability and function …
From telomere to telomere: The transcriptional and epigenetic state of human repeat elements
SJ Hoyt, JM Storer, GA Hartley, PGS Grady… - Science, 2022 - science.org
Mobile elements and repetitive genomic regions are sources of lineage-specific genomic
innovation and uniquely fingerprint individual genomes. Comprehensive analyses of such …
innovation and uniquely fingerprint individual genomes. Comprehensive analyses of such …
[HTML][HTML] Antibody evasion of SARS-CoV-2 Omicron BA. 1, BA. 1.1, BA. 2, and BA. 3 sub-lineages
Summary The SARS-CoV-2 Omicron variant has evolved into four sub-lineages—BA. 1, BA.
1.1, BA. 2, and BA. 3—with BA. 2 becoming dominant worldwide. We and others have …
1.1, BA. 2, and BA. 3—with BA. 2 becoming dominant worldwide. We and others have …
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
Comparative analysis of molecular sequence data is essential for reconstructing the
evolutionary histories of species and inferring the nature and extent of selective forces …
evolutionary histories of species and inferring the nature and extent of selective forces …