SLN and NLC for topical, dermal, and transdermal drug delivery

EB Souto, I Baldim, WP Oliveira, R Rao… - Expert opinion on …, 2020 - Taylor & Francis
Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting
route for drug delivery. In general, small molecules are able to penetrate the stratum …

[HTML][HTML] Nanotoxicology and nanosafety: Safety-by-design and testing at a glance

A Zielińska, B Costa, MV Ferreira, D Miguéis… - International journal of …, 2020 - mdpi.com
This review offers a systematic discussion about nanotoxicology and nanosafety associated
with nanomaterials during manufacture and further biomedical applications. A detailed …

Linalool bioactive properties and potential applicability in drug delivery systems

I Pereira, P Severino, AC Santos, AM Silva… - Colloids and Surfaces B …, 2018 - Elsevier
The medicinal properties of essential oils from aromatic plants are known since antiquity.
Currently, the technological innovation enabled the reinvention of the ancient plant …

Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers–a systematic review of in vitro data

S Doktorovova, EB Souto, AM Silva - European Journal of Pharmaceutics …, 2014 - Elsevier
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were developed as
alternative to other colloidal carriers. They were designed to overcome lipid nanoemulsions …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

Nanomedicines for the delivery of antimicrobial peptides (AMPs)

MC Teixeira, C Carbone, MC Sousa, M Espina… - Nanomaterials, 2020 - mdpi.com
Microbial infections are still among the major public health concerns since several yeasts
and fungi, and other pathogenic microorganisms, are responsible for continuous growth of …

[HTML][HTML] Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals

EB Souto, AR Fernandes, C Martins-Gomes… - Applied Sciences, 2020 - mdpi.com
Featured Application The loading of pharmaceuticals and cosmeceuticals into
nanomaterials is discussed as new formulations for potential treatment of age-related skin …

Cationic surfactants: Self-assembly, structure-activity correlation and their biological applications

LY Zakharova, TN Pashirova, S Doktorovova… - … Journal of Molecular …, 2019 - mdpi.com
The development of biotechnological protocols based on cationic surfactants is a modern
trend focusing on the fabrication of antimicrobial and bioimaging agents, supramolecular …

Potential of lipid nanoparticles (SLNs and NLCs) in enhancing oral bioavailability of drugs with poor intestinal permeability

S Talegaonkar, A Bhattacharyya - Aaps Pharmscitech, 2019 - Springer
Lipid-based drug delivery systems has become a popular choice for oral delivery of
lipophilic drugs with dissolution rate limited oral absorption. Lipids are known to enhance …

In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery

S Jose, SS Anju, TA Cinu, NA Aleykutty… - International journal of …, 2014 - Elsevier
Resveratrol is a potent anticancer. However, because of its low half-life (< 0.25 h) the
molecule is difficult to achieve the therapeutic concentration at the site of action. The aim of …