Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

In response to myocardial infarction (MI), cardiac macrophages regulate inflammation and
scar formation. We hypothesized that macrophages undergo polarization state changes over …

Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …

Optimal healing of damaged tissue following myocardial infarction (MI) requires a
coordinated cellular response that can be divided into three phases: inflammatory …

Periodontitis is an incredibly prevalent chronic inflammatory disease, which results in the
destruction of tooth supporting structures. However, in addition to causing tooth and alveolar …

Cardiac fibroblasts are the major producers of extracellular matrix (ECM) to form infarct scar.
We hypothesized that fibroblasts undergo a spectrum of phenotype states over the course of …

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide. Most
cardiovascular deaths are caused by ischaemic heart diseases such as myocardial …

Periodontal disease (PD) and cardiovascular disease (CVD) are highly prevalent in the
modern community. Both pathologies are chronic inflammatory disorders, which are …

Background: Proteolytically released extracellular matrix (ECM) fragments, matricryptins, are
biologically active and play important roles in wound healing. Following myocardial …