Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Collagen hydrogels are among​ the most well-studied platforms for drug delivery and in situ
tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility …

Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …

Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Tissues consist of cells and their surrounding extracellular matrix (ECM). Cell–ECM
interactions play crucial roles in embryonic development, differentiation, tissue remodeling …

Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

Diabetic foot ulcers (DFUs) have become one of the important causes of mortality and
morbidity in patients with diabetes, and they are also a common cause of hospitalization …

In patients with breast cancer, lower bone mineral density increases the risk of bone
metastasis. Although the relationship between bone-matrix mineralization and tumour-cell …

The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …