Spices for prevention and treatment of cancers

J Zheng, Y Zhou, Y Li, DP Xu, S Li, HB Li - Nutrients, 2016 - mdpi.com
Spices have been widely used as food flavorings and folk medicines for thousands of years.
Numerous studies have documented the antioxidant, anti-inflammatory and …

[HTML][HTML] Thymoquinone: A novel strategy to combat cancer: A review

M Imran, A Rauf, IA Khan, M Shahbaz… - Biomedicine & …, 2018 - Elsevier
The higher consumption of fruit, herbs, spices, and vegetables is well known and practical
strategy to cure human cancers owing to their presence of bioactive compounds. Among …

[HTML][HTML] Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

MA Khan, M Tania, S Fu, J Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this
review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of …

[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects

A Ahmad, RK Mishra, A Vyawahare, A Kumar… - Saudi Pharmaceutical …, 2019 - Elsevier
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …

Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa

AF Majdalawieh, MW Fayyad… - Critical reviews in food …, 2017 - Taylor & Francis
Over the past two decades, studies have documented the wide-range anti-cancer effects of
Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active …

Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Combating breast cancer using combination therapy with 3 phytochemicals: Piperine, sulforaphane, and thymoquinone

MZ Aumeeruddy, MF Mahomoodally - Cancer, 2019 - Wiley Online Library
Despite the significant advances in screening methods for early diagnosis, breast cancer
remains a global threat and continues to be the leading cancer diagnosed in women …

Evaluation of carum-loaded niosomes on breast cancer cells: Physicochemical properties, in vitro cytotoxicity, flow cytometric, DNA fragmentation and cell migration …

M Barani, M Mirzaei, M Torkzadeh-Mahani… - Scientific reports, 2019 - nature.com
Thymoquinone (TQ), a phytochemical compound found in Carum carvil seeds (C. carvil),
has a lot of applications in medical especially cancer therapy. However, TQ has a …

[HTML][HTML] Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches

H Shabani, MH Karami, J Kolour, Z Sayyahi… - Biomedicine & …, 2023 - Elsevier
The rising incidence of breast cancer has been a significant source of concern in the
medical community. Regarding the adverse effects and consequences of current treatments …

Mechanisms of thymoquinone hepatorenal protection in methotrexate‐induced toxicity in rats

AAK El-Sheikh, MA Morsy, AM Abdalla… - Mediators of …, 2015 - Wiley Online Library
To investigate mechanisms by which thymoquinone (TQ) can prevent methotrexate‐(MTX‐)
induced hepatorenal toxicity, TQ (10 mg/kg) was administered orally for 10 days. In …