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Chemotherapy: a double-edged sword in cancer treatment
N Behranvand, F Nasri, R Zolfaghari Emameh… - Cancer immunology …, 2022 - Springer
Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …
has not been as efficient in the eradication of all cancer cells as been expected. The …
Immunotherapeutic approaches for small-cell lung cancer
Immune-checkpoint inhibitors (ICIs) are approved in the first-line and third-line settings for
patients with extensive-stage or relapsed small-cell lung cancer (SCLC), respectively. In the …
patients with extensive-stage or relapsed small-cell lung cancer (SCLC), respectively. In the …
[HTML][HTML] Sintilimab plus platinum and gemcitabine as first-line treatment for advanced or metastatic squamous NSCLC: results from a randomized, double-blind, phase …
C Zhou, L Wu, Y Fan, Z Wang, L Liu, G Chen… - Journal of Thoracic …, 2021 - Elsevier
Introduction The standard chemotherapy for squamous NSCLC (sqNSCLC) includes
platinum plus gemcitabine. Sintilimab, an anti–programmed cell death protein 1 antibody …
platinum plus gemcitabine. Sintilimab, an anti–programmed cell death protein 1 antibody …
Radiotherapy combination opportunities leveraging immunity for the next oncology practice
FG Herrera, J Bourhis, G Coukos - CA: a cancer journal for …, 2017 - Wiley Online Library
Approximately one‐half of patients with newly diagnosed cancer and many patients with
persistent or recurrent tumors receive radiotherapy (RT), with the explicit goal of eliminating …
persistent or recurrent tumors receive radiotherapy (RT), with the explicit goal of eliminating …
Nivolumab in combination with platinum‐based doublet chemotherapy for first-line treatment of advanced non–small-cell lung cancer
Purpose Nivolumab, a fully human immunoglobulin G4 programmed death-1 immune
checkpoint inhibitor antibody, has demonstrated improved survival in previously treated …
checkpoint inhibitor antibody, has demonstrated improved survival in previously treated …
Development of peptide‐based vaccines for cancer
Peptides cancer vaccines are designed based on the epitope peptides that can elicit
humoral and cellular immune responses targeting tumor‐associated antigens (TAAs) or …
humoral and cellular immune responses targeting tumor‐associated antigens (TAAs) or …
Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer
L Bracci, G Schiavoni, A Sistigu… - Cell Death & …, 2014 - nature.com
Conventional anticancer chemotherapy has been historically thought to act through direct
killing of tumor cells. This concept stems from the fact that cytotoxic drugs interfere with DNA …
killing of tumor cells. This concept stems from the fact that cytotoxic drugs interfere with DNA …
Tumor-homing and immune-reprogramming cellular nanovesicles for photoacoustic imaging-guided phototriggered precise chemoimmunotherapy
Many studies have focused on develo** effective therapeutic strategies to selectively
destroy primary tumors, eliminate metastatic lesions, and prevent tumor recurrence with …
destroy primary tumors, eliminate metastatic lesions, and prevent tumor recurrence with …
[HTML][HTML] A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance
J Zhou, N Lyu, Q Wang, M Yang, ET Kimchi, K Cheng… - Cancer letters, 2023 - Elsevier
Abstract Tumor-associated macrophages (TAMs), as a major and essential component of
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …
ROS-generating TiO2 nanoparticles for non-invasive sonodynamic therapy of cancer
The non-invasive photodynamic therapy has been limited to treat superficial tumours,
primarily ascribed to poor tissue penetration of light as the energy source. Herein, we …
primarily ascribed to poor tissue penetration of light as the energy source. Herein, we …